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  • Robert Cross
2019

Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model

Satterfield, B. A., Borisevich, V., Foster, S. L., Rodriguez, S. E., Cross, R. W., Fenton, K., Agans, K. N., Basler, C. F., Geisbert, T. W. & Mire, C. E., Dec 1 2019, In : Scientific reports. 9, 1, 16710.

Research output: Contribution to journalArticle

Open Access

Antibody therapy for Lassa fever

Cross, R. W., Hastie, K. M., Mire, C. E., Robinson, J. E., Geisbert, T. W., Branco, L. M., Ollmann Saphire, E. & Garry, R. F., Aug 2019, In : Current Opinion in Virology. 37, p. 97-104 8 p.

Research output: Contribution to journalReview article

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

Bornholdt, Z. A., Herbert, A. S., Mire, C. E., He, S., Cross, R. W., Wec, A. Z., Abelson, D. M., Geisbert, J. B., James, R. M., Rahim, M. N., Zhu, W., Borisevich, V., Banadyga, L., Gunn, B. M., Agans, K. N., Wirchnianski, A. S., Goodwin, E., Tierney, K., Shestowsky, W. S., Bohorov, O. & 13 others, Bohorova, N., Velasco, J., Ailor, E., Kim, D., Pauly, M. H., Whaley, K. J., Alter, G., Walker, L. M., Chandran, K., Zeitlin, L., Qiu, X., Geisbert, T. W. & Dye, J. M., Jan 9 2019, In : Cell Host and Microbe. 25, 1, p. 49-58.e5

Research output: Contribution to journalArticle

18 Scopus citations

Author Correction: Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants (Scientific Reports, (2017), 7, 1, (9730), 10.1038/s41598-017-09963-y)

Versteeg, K., Menicucci, A. R., Woolsey, C., Mire, C., Geisbert, J. B., Cross, R., Agans, K. N., Jeske, D., Messaoudi, I. & Geisbert, T., Dec 1 2019, In : Scientific reports. 9, 1, 7329.

Research output: Contribution to journalComment/debate

Open Access

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge

Woolsey, C., Menicucci, A. R., Cross, R., Luthra, P., Agans, K. N., Borisevich, V., Geisbert, J. B., Mire, C., Fenton, K. A., Jankeel, A., Anand, S., Ebihara, H., Geisbert, T., Messaoudi, I. & Basler, C. F., Sep 17 2019, In : Cell Reports. 28, 12, p. 3032-3046.e6

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization

Hastie, K. M., Cross, R. W., Harkins, S. S., Zandonatti, M. A., Koval, A. P., Heinrich, M. L., Rowland, M. M., Robinson, J. E., Geisbert, T. W., Garry, R. F., Branco, L. M. & Saphire, E. O., Aug 8 2019, In : Cell. 178, 4, p. 1004-1015.e14

Research output: Contribution to journalArticle

1 Scopus citations

Use of reverse genetics to inform Ebola outbreak responses

Cross, R. W. & Geisbert, T. W., Sep 2019, In : The Lancet Infectious Diseases. 19, 9, p. 925-927 3 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever

Rodriguez, S. E., Cross, R. W., Fenton, K. A., Bente, D. A., Mire, C. E. & Geisbert, T. W., Dec 1 2019, In : Scientific reports. 9, 1, 7755.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2018

Comparative Transcriptomics in Ebola Makona-Infected Ferrets, Nonhuman Primates, and Humans

Cross, R., Speranza, E., Borisevich, V., Widen, S., Wood, T., Shim, R. S., Adams, R. D., Gerhardt, D. M., Bennett, R. S., Honko, A. N., Johnson, J. C., Hensley, L. E., Geisbert, T. & Connor, J. H., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S486-S495

Research output: Contribution to journalArticle

8 Scopus citations

Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates

Gilchuk, P., Mire, C., Geisbert, J. B., Agans, K. N., Deer, D. J., Cross, R., Slaughter, J. C., Flyak, A. I., Mani, J., Pauly, M. H., Velasco, J., Whaley, K. J., Zeitlin, L., Geisbert, T. & Crowe, J. E., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S565-S573

Research output: Contribution to journalArticle

1 Scopus citations

Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever

Boisen, M. L., Hartnett, J. N., Shaffer, J. G., Goba, A., Momoh, M., Sandi, J. D., Fullah, M., Nelson, D. K. S., Bush, D. J., Rowland, M. M., Heinrich, M. L., Koval, A. P., Cross, R., Barnes, K. G., Lachenauer, A. E., Lin, A. E., Nekoui, M., Kotliar, D., Winnicki, S. M., Siddle, K. J. & 18 others, Gbakie, M., Fonnie, M., Koroma, V. J., Kanneh, L., Kulakosky, P. C., Hastie, K. M., Wilson, R. B., Andersen, K. G., Folarin, O. O., Happi, C. T., Sabeti, P. C., Geisbert, T., Saphire, E. O., Khan, S. H., Grant, D. S., Schieffelin, J. S., Branco, L. M. & Garry, R. F., Dec 1 2018, In : Scientific Reports. 8, 1, 5939.

Research output: Contribution to journalArticle

9 Scopus citations

Marburg and Ravn Viruses Fail to Cause Disease in the Domestic Ferret (Mustela putorius furo)

Cross, R., Mire, C., Agans, K. N., Borisevich, V., Fenton, K. A. & Geisbert, T., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S448-S452

Research output: Contribution to journalArticle

6 Scopus citations

Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates

Woolsey, C., Geisbert, J. B., Matassov, D., Agans, K. N., Borisevich, V., Cross, R., Deer, D. J., Fenton, K. A., Eldridge, J. H., Mire, C. & Geisbert, T., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S582-S587

Research output: Contribution to journalArticle

5 Scopus citations

Post-exposure treatments for Ebola and Marburg virus infections

Cross, R. W., Mire, C. E., Feldmann, H. & Geisbert, T. W., Jun 1 2018, In : Nature Reviews Drug Discovery. 17, 6, p. 413-434 22 p.

Research output: Contribution to journalReview article

47 Scopus citations

Small animal models of filovirus disease: recent advances and future directions

Cross, R., Fenton, K. A. & Geisbert, T., Nov 2 2018, In : Expert Opinion on Drug Discovery. 13, 11, p. 1027-1040 14 p.

Research output: Contribution to journalReview article

4 Scopus citations
2017

ELISA methods for the detection of ebolavirus infection

Cross, R. & Ksiazek, T., 2017, Methods in Molecular Biology. Humana Press Inc., Vol. 1628. p. 363-372 10 p. (Methods in Molecular Biology; vol. 1628).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever

Mire, C. E., Cross, R. W., Geisbert, J. B., Borisevich, V., Agans, K. N., Deer, D. J., Heinrich, M. L., Rowland, M. M., Goba, A., Momoh, M., Boisen, M. L., Grant, D. S., Fullah, M., Khan, S. H., Fenton, K. A., Robinson, J. E., Branco, L. M., Garry, R. F. & Geisbert, T. W., Oct 1 2017, In : Nature Medicine. 23, 10, p. 1146-1149 4 p.

Research output: Contribution to journalArticle

35 Scopus citations

Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants

Versteeg, K., Menicucci, A. R., Woolsey, C., Mire, C., Geisbert, J. B., Cross, R., Agans, K. N., Jeske, D., Messaoudi, I. & Geisbert, T., Dec 1 2017, In : Scientific Reports. 7, 1, 9730.

Research output: Contribution to journalArticle

13 Scopus citations

Production of antigens for ELISA

Cross, R. & Ksiazek, T., 2017, Methods in Molecular Biology. Humana Press Inc., Vol. 1628. p. 353-362 10 p. (Methods in Molecular Biology; vol. 1628).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease

Thi, E. P., Mire, C., Lee, A. C. H., Geisbert, J. B., Ursic-Bedoya, R., Agans, K. N., Robbins, M., Deer, D. J., Cross, R., Kondratowicz, A. S., Fenton, K. A., MacLachlan, I. & Geisbert, T., Dec 1 2017, In : Journal of Clinical Investigation. 127, 12, p. 4437-4448 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Transcriptome analysis of circulating immune cell subsets highlight the role of monocytes in Zaire Ebola Virus Makona pathogenesis

Menicucci, A. R., Versteeg, K., Woolsey, C., Mire, C., Geisbert, J. B., Cross, R., Agans, K. N., Jankeel, A., Geisbert, T. & Messaoudi, I., Oct 4 2017, In : Frontiers in Immunology. 8, OCT, 1372.

Research output: Contribution to journalArticle

16 Scopus citations
2016

Analytical Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection

Cross, R. W., Boisen, M. L., Millett, M. M., Nelson, DI. S., Oottamasathien, D., Hartnett, J. N., Jones, A. B., Goba, A., Momoh, M., Fullah, M., Bornholdt, Z. A., Fusco, M. L., Abelson, D. M., Oda, S., Brown, B. L., Pham, H., Rowland, M. M., Agans, K. N., Geisbert, J. B., Heinrich, M. L. & 14 others, Kulakosky, P. C., Shaffer, J. G., Schieffelin, J. S., Kargbo, B., Gbetuwa, M., Gevao, S. M., Wilson, R. B., Saphire, E. O., Pitts, K. R., Khan, S. H., Grant, D. S., Geisbert, T. W., Branco, L. M. & Garry, R. F., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S210-S217

Research output: Contribution to journalArticle

17 Scopus citations

An Outbreak of Ebola Virus Disease in the Lassa Fever Zone

Goba, A., Khan, S. H., Fonnie, M., Fullah, M., Moigboi, A., Kovoma, A., Sinnah, V., Yoko, N., Rogers, H., Safai, S., Momoh, M., Koroma, V., Kamara, F. K., Konowu, E., Yillah, M., French, I., Mustapha, I., Kanneh, F., Foday, M., McCarthy, H. & 64 others, Kallon, T., Kallon, M., Naiebu, J., Sellu, J., Jalloh, A. A., Gbakie, M., Kanneh, L., Massaly, J. L. B., Kargbo, D., Kargbo, B., Vandi, M., Gbetuwa, M., Gevao, S. M., Sandi, J. D., Jalloh, S. C., Grant, D. S., Blyden, S. O., Crozier, I., Schieffelin, J. S., McLellan, S. L., Jacob, S. T., Boisen, M. L., Hartnett, J. N., Cross, R. W., Branco, L. M., Andersen, K. G., Yozwiak, N. L., Gire, S. K., Tariyal, R., Park, D. J., Haislip, A. M., Bishop, C. M., Melnik, L. I., Gallaher, W. R., Wimley, W. C., He, J., Shaffer, J. G., Sullivan, B. M., Grillo, S., Oman, S., Garry, C. E., Edwards, D. R., McCormick, S. J., Elliott, D. H., Rouelle, J. A., Kannadka, C. B., Reyna, A. A., Bradley, B. T., Yu, H., Yenni, R. E., Hastie, K. M., Geisbert, J. B., Kulakosky, P. C., Wilson, R. B., Oldstone, M. B. A., Pitts, K. R., Henderson, L. A., Robinson, J. E., Geisbert, T. W., Saphire, E. O., Happi, C. T., Asogun, D. A., Sabeti, P. C. & Garry, R. F., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S110-S121

Research output: Contribution to journalArticle

18 Scopus citations

Field Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection

Boisen, M. L., Cross, R. W., Hartnett, J. N., Goba, A., Momoh, M., Fullah, M., Gbakie, M., Safa, S., Fonnie, M., Baimba, F., Koroma, V. J., Geisbert, J. B., McCormick, S., Nelson, DI. K. S., Millett, M. M., Oottamasathien, D., Jones, A. B., Pham, H., Brown, B. L., Shaffer, J. G. & 11 others, Schieffelin, J. S., Kargbo, B., Gbetuwa, M., Gevao, S. M., Wilson, R. B., Pitts, K. R., Geisbert, T. W., Branco, L. M., Khan, S. H., Grant, D. S. & Garry, R. F., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S203-S209

Research output: Contribution to journalArticle

16 Scopus citations

Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits

Robinson, J. E., Hastie, K. M., Cross, R. W., Yenni, R. E., Elliott, D. H., Rouelle, J. A., Kannadka, C. B., Smira, A. A., Garry, C. E., Bradley, B. T., Yu, H., Shaffer, J. G., Boisen, M. L., Hartnett, J. N., Zandonatti, M. A., Rowland, M. M., Heinrich, M. L., Martinez-Sobrido, L., Cheng, B., De La Torre, J. C. & 30 others, Andersen, K. G., Goba, A., Momoh, M., Fullah, M., Gbakie, M., Kanneh, L., Koroma, V. J., Fonnie, R., Jalloh, S. C., Kargbo, B., Vandi, M. A., Gbetuwa, M., Ikponmwosa, O., Asogun, D. A., Okokhere, P. O., Follarin, O. A., Schieffelin, J. S., Pitts, K. R., Geisbert, J. B., Kulakoski, P. C., Wilson, R. B., Happi, C. T., Sabeti, P. C., Gevao, S. M., Khan, S. H., Grant, D. S., Geisbert, T. W., Saphire, E. O., Branco, L. M. & Garry, R. F., May 10 2016, In : Nature communications. 7, 11544.

Research output: Contribution to journalArticle

50 Scopus citations

Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets

Satterfield, B. A., Cross, R. W., Fenton, K. A., Borisevich, V., Agans, K. N., Deer, D. J., Graber, J., Basler, C. F., Geisbert, T. W. & Mirea, C. E., 2016, In : Journal of virology. 90, 14, p. 6326-6343 18 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy

Mire, C., Satterfield, B. A., Geisbert, J. B., Agans, K. N., Borisevich, V., Yan, L., Chan, Y. P., Cross, R., Fenton, K. A., Broder, C. C. & Geisbert, T., Aug 3 2016, In : Scientific Reports. 6, 30916.

Research output: Contribution to journalArticle

39 Scopus citations

The domestic ferret (mustela putorius furo) as a lethal infection model for 3 species of ebolavirus

Cross, R., Mire, C., Borisevich, V., Geisbert, J. B., Fenton, K. A. & Geisbert, T., Aug 15 2016, In : Journal of Infectious Diseases. 214, 4, p. 565-569 5 p.

Research output: Contribution to journalArticle

40 Scopus citations

Treatment of Lassa virus infection in outbred guinea pigs with first-in-class human monoclonal antibodies

Cross, R., Mire, C., Branco, L. M., Geisbert, J. B., Rowland, M. M., Heinrich, M. L., Goba, A., Momoh, M., Grant, D. S., Fullah, M., Khan, S. H., Robinson, J. E., Geisbert, T. & Garry, R. F., Sep 1 2016, In : Antiviral Research. 133, p. 218-222 5 p.

Research output: Contribution to journalArticle

26 Scopus citations