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  • 2020
  • 2019
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  • 2017
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Author

  • Satya Prakash
2020
Open Access
2019

Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme

Jain, R., Rice, W. J., Malik, R., Johnson, R. E., Prakash, L., Prakash, S., Ubarretxena-Belandia, I. & Aggarwal, A. K., Oct 1 2019, In : Nature Structural and Molecular Biology. 26, 10, p. 955-962 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

DNA polymerase θ accomplishes translesion synthesis opposite 1, N 6 -ethenodeoxyadenosine with a remarkably high fidelity in human cells

Yoon, J. H., Johnson, R. E., Prakash, L. & Prakash, S., Mar 1 2019, In : Genes and Development. 33, 5-6, p. 282-287 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Error-Prone Replication through UV Lesions by DNA Polymerase θ Protects against Skin Cancers

Yoon, J. H., McArthur, M. J., Park, J., Basu, D., Wakamiya, M., Prakash, L. & Prakash, S., Mar 7 2019, In : Cell. 176, 6, p. 1295-1309.e15

Research output: Contribution to journalArticle

12 Scopus citations

Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η

Rechkoblit, O., Johnson, R. E., Buku, A., Prakash, L., Prakash, S. & Aggarwal, A. K., Dec 1 2019, In : Scientific reports. 9, 1, 16400.

Research output: Contribution to journalArticle

Open Access

Translesion synthesis DNA polymerases η, ι, and ν promote mutagenic replication through the anticancer nucleoside cytarabine

Yoon, J. H., Choudhury, J. R., Prakash, L. & Prakash, S., Dec 13 2019, In : Journal of Biological Chemistry. 294, 50, p. 19048-19054 7 p.

Research output: Contribution to journalArticle

2018

Genetic control of predominantly error-free replication through an acrolein-derived minor-groove DNA adduct

Yoon, J. H., Hodge, R. P., Hackfeld, L. C., Park, J., Choudhury, J. R., Prakash, S. & Prakash, L., Jan 1 2018, In : Journal of Biological Chemistry. 293, 8, p. 2949-2958 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Structural basis for polymerase η–promoted resistance to the anticancer nucleoside analog cytarabine

Rechkoblit, O., Choudhury, J. R., Buku, A., Prakash, L., Prakash, S. & Aggarwal, A. K., Dec 1 2018, In : Scientific Reports. 8, 1, 12702.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-l

Jain, R., Choudhury, J. R., Buku, A., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Mar 8 2017, In : Scientific reports. 7, 43904.

Research output: Contribution to journalArticle

7 Scopus citations

Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA adduct 3-deaza-3-methyladenine

Yoon, J. H., Choudhury, J. R., Park, J., Prakash, S. & Prakash, L., Nov 10 2017, In : Journal of Biological Chemistry. 292, 45, p. 18682-18688 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Human DNA polymerase α in binary complex with a DNA: DNA template-primer

Coloma, J., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Apr 1 2016, In : Scientific Reports. 6, 23784.

Research output: Contribution to journalArticle

13 Scopus citations

Response to Burgers et al.

Johnson, R. E., Klassen, R., Prakash, L. & Prakash, S., Feb 18 2016, In : Molecular Cell. 61, 4, p. 494-495 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Structure and mechanism of human PrimPol, a DNA polymerase with primase activity

Rechkoblit, O., Gupta, Y. K., Malik, R., Rajashankar, K. R., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Oct 1 2016, In : Science advances. 2, 10, e1601317.

Research output: Contribution to journalArticle

28 Scopus citations