Rabies viruses from 2 types of bats were inoculated intracerebrally into laboratory mice. The reactions of the mice differed markedly. Those inoculated with virus from a Mexican freetail bat, Tadarida brasiliensis mexicana, died a violent death after an incubation of 4 to 5 days. The pathology was marked, with much neuronal destruction noted. Those mice inoculated with virus from a vampire bat, Desmodus rotundus, died after incubation periods similar to those noted after inoculation of common 'street' viruses, i.e., 7 days or more. The pathology corresponded to the limited amount usually seen after death from 'street' virus.
ASJC Scopus subject areas
- Clinical Biochemistry
- Molecular Biology
- Pathology and Forensic Medicine