A case of Guillain-Barre syndrome with immunologic abnormalities

C. J. Froelich, R. P. Searles, L. E. Davis, James Goodwin

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Guillain-Barre syndrome and the nephrotic syndrome developed in a patient simultaneously. Analysis of renal biopsy by light, immunofluorescent, and electron microscopy showed lipoid nephrosis. T-cell lymphocytopenia, lymphocytotoxic antibodies, depressed lymphocyte mitogenesis, and anergy also complicated the illness. The immunologic abnormalities resolved when the polyradiculoneuritis and lipoid nephrosis remitted. This previously undescribed association illustrates the occurrence of two postulated cell-mediated autoimmune disorders despite the presence of depressed cell-mediated immunity.

Original languageEnglish (US)
Pages (from-to)563-565
Number of pages3
JournalAnnals of Internal Medicine
Volume93
Issue number4
StatePublished - 1980
Externally publishedYes

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Lipoid Nephrosis
Guillain-Barre Syndrome
Polyradiculoneuropathy
Antilymphocyte Serum
Nephrotic Syndrome
Cellular Immunity
Electron Microscopy
Lymphocytes
T-Lymphocytes
Kidney
Biopsy
Light
T-Lymphocytopenia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Froelich, C. J., Searles, R. P., Davis, L. E., & Goodwin, J. (1980). A case of Guillain-Barre syndrome with immunologic abnormalities. Annals of Internal Medicine, 93(4), 563-565.

A case of Guillain-Barre syndrome with immunologic abnormalities. / Froelich, C. J.; Searles, R. P.; Davis, L. E.; Goodwin, James.

In: Annals of Internal Medicine, Vol. 93, No. 4, 1980, p. 563-565.

Research output: Contribution to journalArticle

Froelich, CJ, Searles, RP, Davis, LE & Goodwin, J 1980, 'A case of Guillain-Barre syndrome with immunologic abnormalities', Annals of Internal Medicine, vol. 93, no. 4, pp. 563-565.
Froelich, C. J. ; Searles, R. P. ; Davis, L. E. ; Goodwin, James. / A case of Guillain-Barre syndrome with immunologic abnormalities. In: Annals of Internal Medicine. 1980 ; Vol. 93, No. 4. pp. 563-565.
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