A case of Guillain-Barre syndrome with immunologic abnormalities

C. J. Froelich; R. P. Searles; L. E. Davis; J. S. Goodwin

doi:10.7326/0003-4819-93-4-563

A case of Guillain-Barre syndrome with immunologic abnormalities

C. J. Froelich, R. P. Searles, L. E. Davis, J. S. Goodwin

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Abstract

Guillain-Barre syndrome and the nephrotic syndrome developed in a patient simultaneously. Analysis of renal biopsy by light, immunofluorescent, and electron microscopy showed lipoid nephrosis. T-cell lymphocytopenia, lymphocytotoxic antibodies, depressed lymphocyte mitogenesis, and anergy also complicated the illness. The immunologic abnormalities resolved when the polyradiculoneuritis and lipoid nephrosis remitted. This previously undescribed association illustrates the occurrence of two postulated cell-mediated autoimmune disorders despite the presence of depressed cell-mediated immunity.

Original language	English (US)
Pages (from-to)	563-565
Number of pages	3
Journal	Annals of internal medicine
Volume	93
Issue number	4
DOIs	https://doi.org/10.7326/0003-4819-93-4-563
State	Published - 1980
Externally published	Yes

ASJC Scopus subject areas

Internal Medicine

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abstract = "Guillain-Barre syndrome and the nephrotic syndrome developed in a patient simultaneously. Analysis of renal biopsy by light, immunofluorescent, and electron microscopy showed lipoid nephrosis. T-cell lymphocytopenia, lymphocytotoxic antibodies, depressed lymphocyte mitogenesis, and anergy also complicated the illness. The immunologic abnormalities resolved when the polyradiculoneuritis and lipoid nephrosis remitted. This previously undescribed association illustrates the occurrence of two postulated cell-mediated autoimmune disorders despite the presence of depressed cell-mediated immunity.",

author = "Froelich, {C. J.} and Searles, {R. P.} and Davis, {L. E.} and Goodwin, {J. S.}",

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AU - Searles, R. P.

AU - Davis, L. E.

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PY - 1980

Y1 - 1980

N2 - Guillain-Barre syndrome and the nephrotic syndrome developed in a patient simultaneously. Analysis of renal biopsy by light, immunofluorescent, and electron microscopy showed lipoid nephrosis. T-cell lymphocytopenia, lymphocytotoxic antibodies, depressed lymphocyte mitogenesis, and anergy also complicated the illness. The immunologic abnormalities resolved when the polyradiculoneuritis and lipoid nephrosis remitted. This previously undescribed association illustrates the occurrence of two postulated cell-mediated autoimmune disorders despite the presence of depressed cell-mediated immunity.

AB - Guillain-Barre syndrome and the nephrotic syndrome developed in a patient simultaneously. Analysis of renal biopsy by light, immunofluorescent, and electron microscopy showed lipoid nephrosis. T-cell lymphocytopenia, lymphocytotoxic antibodies, depressed lymphocyte mitogenesis, and anergy also complicated the illness. The immunologic abnormalities resolved when the polyradiculoneuritis and lipoid nephrosis remitted. This previously undescribed association illustrates the occurrence of two postulated cell-mediated autoimmune disorders despite the presence of depressed cell-mediated immunity.

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A case of Guillain-Barre syndrome with immunologic abnormalities

Abstract

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