The vertebrate lens is composed of two distinct cell types, the epithelial cell and the fiber cell. α-Crystallin, a structural protein found in both cell types, is composed of four subunits (αA1, αA2, αB1, and αB2). In the epithelial cells the α-crystallin consists mainly of αA2 and αB2 with trace amounts of αA1 and αB1. In the fiber cell there is a large increase in the amount of αA1 and αB1 subunits. This quantitative increase in two specific subunits is related to the process of cellular growth and differentiation in the vertebrate lens.
|Original language||English (US)|
|Number of pages||6|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Oct 23 1970|
ASJC Scopus subject areas
- Molecular Biology