A comparative trial of ceftizoxime versus cefamandole in the treatment of acute urinary tract infections

Alfred Lea, A. W. Sudan, P. L. Gould, L. O. Gentry

Research output: Contribution to journalArticle

3 Scopus citations


The results of this study demonstrate that ceftizoxime, a new β-lactamase-stable cephalosporin is as effective as cefamandole for eradicating susceptible pathogens from the urine of adult females with a clinical diagnosis of pyelonephritis. The effective daily dosage of ceftizoxime in this study was half that of cefamandole. There was no difference in the observed incidence of adverse drug reactions to each agent.

Original languageEnglish (US)
Pages (from-to)261-363
Number of pages103
JournalJournal of Antimicrobial Chemotherapy
Issue numberSuppl. C
StatePublished - 1982
Externally publishedYes


ASJC Scopus subject areas

  • Microbiology
  • Pharmacology

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