A Comparison of Erysipelothrix rhusiopathiae Bacteremia With and Without Endocarditis in Frequent Fish Handlers

J. Patrik Hornak, Maranatha R. McLean, Camille M. Webb, Philip Keiser

Research output: Contribution to journalArticle

Abstract

A facultatively anaerobic gram-positive bacillus, Erysipelothrix rhusiopathiae is widely present in the environment and also as a commensal and pathogenic organism associated with livestock, birds, and fish. Invasive infections in humans are rare, classically affect patients with exposures to animal products, and frequently progress to include endocarditis. Here we present our successful experience of treating 2 patients with E. rhusiopathiae bacteremia, both frequently exposed to fish. One patient presented in new-onset heart failure after a protracted illness and was found to have subacute aortic and mitral valve endocarditis successfully treated with surgical valve replacement and prolonged intravenous penicillin therapy. The other patient had acute uncomplicated bacteremia responsive to ceftriaxone followed by step-down treatment with oral penicillin, the first published report using such regimen. Our experience highlights the spectrum of clinical disease seen in E. rhusiopathiae bacteremia and offers new perspectives to optimize treatment for these patients.

Original languageEnglish (US)
Pages (from-to)175-177
Number of pages3
JournalInfectious Diseases in Clinical Practice
Volume27
Issue number3
DOIs
StatePublished - May 1 2019

Fingerprint

Erysipelothrix
Bacteremia
Endocarditis
Penicillins
Fishes
Ceftriaxone
Livestock
Aortic Valve
Mitral Valve
Surgical Instruments
Bacillus
Birds
Therapeutics
Heart Failure
Infection

Keywords

  • bacteremia
  • bloodstream infection
  • ceftriaxone
  • Erysipelothrix rhusiopathiae
  • gram-positive organism
  • infective endocarditis
  • occupational pathogen
  • penicillin
  • recreational exposure

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

A Comparison of Erysipelothrix rhusiopathiae Bacteremia With and Without Endocarditis in Frequent Fish Handlers. / Hornak, J. Patrik; McLean, Maranatha R.; Webb, Camille M.; Keiser, Philip.

In: Infectious Diseases in Clinical Practice, Vol. 27, No. 3, 01.05.2019, p. 175-177.

Research output: Contribution to journalArticle

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