A comparison of hemoglobin A1(c) in human and baboon blood

J. B. Alperin, P. A. Dow, L. C. Stout

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Abstract

Cation exchange chromatography was performed on hemolysates prepared from human and baboon (Papio anubis) blood. In humans with diabetes mellitus and in baboons with pancreatectomy induced diabetes mellitus there were significant increases in Hbs A1, A(1c) and A(1a) + A(1b). The quantity of Hb A1 and Hb A(1c) in nondiabetic baboons was approximately one-half the quantity of Hb A1 and Hb A(1c) in nondiabetic humans. These differences may be explained by the differences in survival time between human and baboon red cells.

Original languageEnglish (US)
Pages (from-to)334-338
Number of pages5
JournalActa Haematologica
Volume61
Issue number6
StatePublished - 1979

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ASJC Scopus subject areas

  • Hematology

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Alperin, J. B., Dow, P. A., & Stout, L. C. (1979). A comparison of hemoglobin A1(c) in human and baboon blood. Acta Haematologica, 61(6), 334-338.