TY - JOUR
T1 - A comparison of postoperative effects of bariatric surgery on medical markers of morbidity
AU - Bonner, Gwen L.
AU - Nagy, Andrew J.
AU - Jupiter, Daniel C.
AU - Rodriguez, Joaquin A.
AU - Symmonds, Richard E.
AU - Carpenter, Robert O.
N1 - Publisher Copyright:
© 2014 Elsevier Inc.All rights reserved.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - Background Bariatric surgery reduces the prevalence of diabetes and improves lipid profiles. Low-density lipoprotein particle (LDL-P) is a more accurate predictor of cardiovascular events than high-density lipoprotein (HDL) and LDL cholesterol. The effects of bariatric procedures on LDL-P have not been previously reported.Methods Two hundred thirty patients undergoing bariatric surgery, including gastric bypass, sleeve gastrectomy, and laparoscopic adjustable gastric band placement at a single institution were included. HDL, LDL, hemoglobin A1c, and LDL-P were measured preoperatively and at 3, 6, and 12 months postoperatively. Weight was recorded at baseline and after 1 year.Results There was a decrease in serum LDL-P levels, averaging 472.58 (P <.0001) over 1 year. HDL levels increased. Hemoglobin A1c and LDL levels declined. On average, patients lost 58% of excess weight.Conclusion LDL-P significantly decreased after bariatric surgery in relation to weight loss. It may be inferred that bariatric surgery decreases the risk of cardiovascular events.
AB - Background Bariatric surgery reduces the prevalence of diabetes and improves lipid profiles. Low-density lipoprotein particle (LDL-P) is a more accurate predictor of cardiovascular events than high-density lipoprotein (HDL) and LDL cholesterol. The effects of bariatric procedures on LDL-P have not been previously reported.Methods Two hundred thirty patients undergoing bariatric surgery, including gastric bypass, sleeve gastrectomy, and laparoscopic adjustable gastric band placement at a single institution were included. HDL, LDL, hemoglobin A1c, and LDL-P were measured preoperatively and at 3, 6, and 12 months postoperatively. Weight was recorded at baseline and after 1 year.Results There was a decrease in serum LDL-P levels, averaging 472.58 (P <.0001) over 1 year. HDL levels increased. Hemoglobin A1c and LDL levels declined. On average, patients lost 58% of excess weight.Conclusion LDL-P significantly decreased after bariatric surgery in relation to weight loss. It may be inferred that bariatric surgery decreases the risk of cardiovascular events.
KW - Bariatric surgery
KW - Cardiovascular risk
KW - Cholesterol
KW - LDL particle
KW - Obesity
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U2 - 10.1016/j.amjsurg.2014.09.005
DO - 10.1016/j.amjsurg.2014.09.005
M3 - Article
C2 - 25440477
AN - SCOPUS:84916595801
SN - 0002-9610
VL - 208
SP - 897
EP - 902
JO - American Journal of Surgery
JF - American Journal of Surgery
IS - 6
ER -