A comparison of postoperative effects of bariatric surgery on medical markers of morbidity

Gwen L. Bonner; Andrew J. Nagy; Daniel C. Jupiter; Joaquin A. Rodriguez; Richard E. Symmonds; Robert O. Carpenter

doi:10.1016/j.amjsurg.2014.09.005

A comparison of postoperative effects of bariatric surgery on medical markers of morbidity

Gwen L. Bonner
, Andrew J. Nagy
, Daniel C. Jupiter
, Joaquin A. Rodriguez
, Richard E. Symmonds
, Robert O. Carpenter

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Background Bariatric surgery reduces the prevalence of diabetes and improves lipid profiles. Low-density lipoprotein particle (LDL-P) is a more accurate predictor of cardiovascular events than high-density lipoprotein (HDL) and LDL cholesterol. The effects of bariatric procedures on LDL-P have not been previously reported.

Methods Two hundred thirty patients undergoing bariatric surgery, including gastric bypass, sleeve gastrectomy, and laparoscopic adjustable gastric band placement at a single institution were included. HDL, LDL, hemoglobin A1c, and LDL-P were measured preoperatively and at 3, 6, and 12 months postoperatively. Weight was recorded at baseline and after 1 year.

Results There was a decrease in serum LDL-P levels, averaging 472.58 (P <.0001) over 1 year. HDL levels increased. Hemoglobin A1c and LDL levels declined. On average, patients lost 58% of excess weight.

Conclusion LDL-P significantly decreased after bariatric surgery in relation to weight loss. It may be inferred that bariatric surgery decreases the risk of cardiovascular events.

Original language	English (US)
Pages (from-to)	897-902
Number of pages	6
Journal	American Journal of Surgery
Volume	208
Issue number	6
DOIs	https://doi.org/10.1016/j.amjsurg.2014.09.005
State	Published - Dec 1 2014
Externally published	Yes

Keywords

Bariatric surgery
Cardiovascular risk
Cholesterol
LDL particle
Obesity

ASJC Scopus subject areas

Surgery

Access to Document

10.1016/j.amjsurg.2014.09.005

Cite this

@article{30c2c1cffc664469af1af9848f92392a,

title = "A comparison of postoperative effects of bariatric surgery on medical markers of morbidity",

abstract = "Background Bariatric surgery reduces the prevalence of diabetes and improves lipid profiles. Low-density lipoprotein particle (LDL-P) is a more accurate predictor of cardiovascular events than high-density lipoprotein (HDL) and LDL cholesterol. The effects of bariatric procedures on LDL-P have not been previously reported.Methods Two hundred thirty patients undergoing bariatric surgery, including gastric bypass, sleeve gastrectomy, and laparoscopic adjustable gastric band placement at a single institution were included. HDL, LDL, hemoglobin A1c, and LDL-P were measured preoperatively and at 3, 6, and 12 months postoperatively. Weight was recorded at baseline and after 1 year.Results There was a decrease in serum LDL-P levels, averaging 472.58 (P <.0001) over 1 year. HDL levels increased. Hemoglobin A1c and LDL levels declined. On average, patients lost 58\% of excess weight.Conclusion LDL-P significantly decreased after bariatric surgery in relation to weight loss. It may be inferred that bariatric surgery decreases the risk of cardiovascular events.",

keywords = "Bariatric surgery, Cardiovascular risk, Cholesterol, LDL particle, Obesity",

author = "Bonner, \{Gwen L.\} and Nagy, \{Andrew J.\} and Jupiter, \{Daniel C.\} and Rodriguez, \{Joaquin A.\} and Symmonds, \{Richard E.\} and Carpenter, \{Robert O.\}",

year = "2014",

month = dec,

day = "1",

doi = "10.1016/j.amjsurg.2014.09.005",

language = "English (US)",

volume = "208",

pages = "897--902",

journal = "American Journal of Surgery",

issn = "0002-9610",

publisher = "Elsevier Inc.",

number = "6",

}

TY - JOUR

T1 - A comparison of postoperative effects of bariatric surgery on medical markers of morbidity

AU - Bonner, Gwen L.

AU - Nagy, Andrew J.

AU - Jupiter, Daniel C.

AU - Rodriguez, Joaquin A.

AU - Symmonds, Richard E.

AU - Carpenter, Robert O.

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Background Bariatric surgery reduces the prevalence of diabetes and improves lipid profiles. Low-density lipoprotein particle (LDL-P) is a more accurate predictor of cardiovascular events than high-density lipoprotein (HDL) and LDL cholesterol. The effects of bariatric procedures on LDL-P have not been previously reported.Methods Two hundred thirty patients undergoing bariatric surgery, including gastric bypass, sleeve gastrectomy, and laparoscopic adjustable gastric band placement at a single institution were included. HDL, LDL, hemoglobin A1c, and LDL-P were measured preoperatively and at 3, 6, and 12 months postoperatively. Weight was recorded at baseline and after 1 year.Results There was a decrease in serum LDL-P levels, averaging 472.58 (P <.0001) over 1 year. HDL levels increased. Hemoglobin A1c and LDL levels declined. On average, patients lost 58% of excess weight.Conclusion LDL-P significantly decreased after bariatric surgery in relation to weight loss. It may be inferred that bariatric surgery decreases the risk of cardiovascular events.

AB - Background Bariatric surgery reduces the prevalence of diabetes and improves lipid profiles. Low-density lipoprotein particle (LDL-P) is a more accurate predictor of cardiovascular events than high-density lipoprotein (HDL) and LDL cholesterol. The effects of bariatric procedures on LDL-P have not been previously reported.Methods Two hundred thirty patients undergoing bariatric surgery, including gastric bypass, sleeve gastrectomy, and laparoscopic adjustable gastric band placement at a single institution were included. HDL, LDL, hemoglobin A1c, and LDL-P were measured preoperatively and at 3, 6, and 12 months postoperatively. Weight was recorded at baseline and after 1 year.Results There was a decrease in serum LDL-P levels, averaging 472.58 (P <.0001) over 1 year. HDL levels increased. Hemoglobin A1c and LDL levels declined. On average, patients lost 58% of excess weight.Conclusion LDL-P significantly decreased after bariatric surgery in relation to weight loss. It may be inferred that bariatric surgery decreases the risk of cardiovascular events.

KW - Bariatric surgery

KW - Cardiovascular risk

KW - Cholesterol

KW - LDL particle

KW - Obesity

UR - https://www.scopus.com/pages/publications/84916595801

UR - https://www.scopus.com/pages/publications/84916595801#tab=citedBy

U2 - 10.1016/j.amjsurg.2014.09.005

DO - 10.1016/j.amjsurg.2014.09.005

M3 - Article

C2 - 25440477

AN - SCOPUS:84916595801

SN - 0002-9610

VL - 208

SP - 897

EP - 902

JO - American Journal of Surgery

JF - American Journal of Surgery

IS - 6

ER -

A comparison of postoperative effects of bariatric surgery on medical markers of morbidity

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this