A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents

Amir P. Tamiz, Paola Conti, Mei Zhang, Kenneth M. Johnson, Alan P. Kozikowski

Research output: Contribution to journal › Article

6 Citations (Scopus)

Abstract

A convenient synthesis of nonsymmetrical bivalent inhibitors of the serotonin transporter is described. The synthesis utilizes polymer-supported reagents that allow for rapid access to novel bivalent ligands without the need for isolation or purification of synthetic intermediates. (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)2741-2743
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume10
Issue number24
StatePublished - Dec 18 2000

Fingerprint

Serotonin Plasma Membrane Transport Proteins
Serotonin Uptake Inhibitors
Polymers
Ligands
Purification

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

Cite this

A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents. / Tamiz, Amir P.; Conti, Paola; Zhang, Mei; Johnson, Kenneth M.; Kozikowski, Alan P.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 10, No. 24, 18.12.2000, p. 2741-2743.

Research output: Contribution to journal › Article

Tamiz, AP, Conti, P, Zhang, M, Johnson, KM & Kozikowski, AP 2000, 'A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents', Bioorganic and Medicinal Chemistry Letters, vol. 10, no. 24, pp. 2741-2743.
Tamiz AP, Conti P, Zhang M, Johnson KM, Kozikowski AP. A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents. Bioorganic and Medicinal Chemistry Letters. 2000 Dec 18;10(24):2741-2743.
Tamiz, Amir P. ; Conti, Paola ; Zhang, Mei ; Johnson, Kenneth M. ; Kozikowski, Alan P. / A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents. In: Bioorganic and Medicinal Chemistry Letters. 2000 ; Vol. 10, No. 24. pp. 2741-2743.
@article{0eb51157743e4f71a55b8602cd56d1f3,
title = "A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents",
abstract = "A convenient synthesis of nonsymmetrical bivalent inhibitors of the serotonin transporter is described. The synthesis utilizes polymer-supported reagents that allow for rapid access to novel bivalent ligands without the need for isolation or purification of synthetic intermediates. (C) 2000 Elsevier Science Ltd.",
author = "Tamiz, {Amir P.} and Paola Conti and Mei Zhang and Johnson, {Kenneth M.} and Kozikowski, {Alan P.}",
year = "2000",
month = "12",
day = "18",
language = "English (US)",
volume = "10",
pages = "2741--2743",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Limited",
number = "24",

}

TY - JOUR

T1 - A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents

AU - Tamiz, Amir P.

AU - Conti, Paola

AU - Zhang, Mei

AU - Johnson, Kenneth M.

AU - Kozikowski, Alan P.

PY - 2000/12/18

Y1 - 2000/12/18

N2 - A convenient synthesis of nonsymmetrical bivalent inhibitors of the serotonin transporter is described. The synthesis utilizes polymer-supported reagents that allow for rapid access to novel bivalent ligands without the need for isolation or purification of synthetic intermediates. (C) 2000 Elsevier Science Ltd.

AB - A convenient synthesis of nonsymmetrical bivalent inhibitors of the serotonin transporter is described. The synthesis utilizes polymer-supported reagents that allow for rapid access to novel bivalent ligands without the need for isolation or purification of synthetic intermediates. (C) 2000 Elsevier Science Ltd.

UR - http://www.scopus.com/inward/record.url?scp=0034684755&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034684755&partnerID=8YFLogxK

M3 - Article

C2 - 11133081

AN - SCOPUS:0034684755

VL - 10

SP - 2741

EP - 2743

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

SN - 0960-894X

IS - 24

ER -

Access to Document