Abstract
A convenient synthesis of nonsymmetrical bivalent inhibitors of the serotonin transporter is described. The synthesis utilizes polymer-supported reagents that allow for rapid access to novel bivalent ligands without the need for isolation or purification of synthetic intermediates. (C) 2000 Elsevier Science Ltd.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2741-2743 |
| Number of pages | 3 |
| Journal | Bioorganic and Medicinal Chemistry Letters |
| Volume | 10 |
| Issue number | 24 |
| DOIs | |
| State | Published - Dec 18 2000 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmaceutical Science
- Drug Discovery
- Clinical Biochemistry
- Organic Chemistry
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Cite this
Tamiz, A. P., Conti, P., Zhang, M., Johnson, K. M., & Kozikowski, A. P. (2000). A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents. Bioorganic and Medicinal Chemistry Letters, 10(24), 2741-2743. https://doi.org/10.1016/S0960-894X(00)00576-X