A critique of clinical equipoise therapeutic misconception in the ethics of clinical trials

Franklin G. Miller, Howard Brody

Research output: Contribution to journalArticle

278 Citations (Scopus)

Abstract

A predominant ethical view holds that physician-investigators should conduct their research with therapeutic intent. And since a physician offering a therapy wouldn't prescribe second-rate treatments, the experimental intervention and the best proven therapy should appear equally effective. "Clinical equipoise" is necessary. But this perspective is flawed. The ethics of research and of therapy are fundamentally different, and clinical equipoise should be abandoned.

Original languageEnglish (US)
Pages (from-to)19-28
Number of pages10
JournalHastings Center Report
Volume33
Issue number3
DOIs
StatePublished - May 2003
Externally publishedYes

Fingerprint

Therapeutic Misconception
Ethics
moral philosophy
Clinical Trials
physician
Therapeutic Human Experimentation
Research Ethics
Physicians
Therapeutics
Research Personnel
boldenone undecylenate
Therapy
Misconceptions

ASJC Scopus subject areas

  • Health(social science)
  • Issues, ethics and legal aspects
  • Health Policy
  • Nursing(all)
  • Medicine (miscellaneous)
  • Social Sciences (miscellaneous)

Cite this

A critique of clinical equipoise therapeutic misconception in the ethics of clinical trials. / Miller, Franklin G.; Brody, Howard.

In: Hastings Center Report, Vol. 33, No. 3, 05.2003, p. 19-28.

Research output: Contribution to journalArticle

Miller, Franklin G. ; Brody, Howard. / A critique of clinical equipoise therapeutic misconception in the ethics of clinical trials. In: Hastings Center Report. 2003 ; Vol. 33, No. 3. pp. 19-28.
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