A double-blind placebo controlled study of a 5% lidocaine/prilocaine cream (EMLA) for topical anesthesia during thermolysis

Richard Wagner, C. A. Flores, L. F. Argo

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

BACKGROUND. Electrolysis and thermolysis are commonly used electrosurgical methods for the permanent destruction of unwanted hair. However, patient fear of pain during treatment may interfere with or even prevent desired treatment of hirsutism on sensitive areas such as the upper lip. OBJECTIVE. This study was conducted to assess the efficacy of EMLA (Eutectic Mixture of Local Anesthetics), a 5% lidocaine/prilocaine cream, as a topically applied local anesthetic during thermolysis on the upper lip. METHODS. A double-blind placebo control study was conducted by the University of Texas Medical Branch thermolysis clinic. Thirty women with idiopathic hirsutism of the upper lip were studied. Pain was measured with a 100 mm visual analog scale (VAS). RESULTS. Total paired VAS score differences comparing the placebo VAS scores to the EMLA VAS scores were significant by paired t-test (P = .0001). Adverse reactions were mild and transient. CONCLUSION. EMLA cream may have multiple applications to the practice of dermatologic surgery, including topically achieved local anesthesia during thermolysis and electrolysis.

Original languageEnglish (US)
Pages (from-to)148-150
Number of pages3
JournalJournal of Dermatologic Surgery and Oncology
Volume20
Issue number2
StatePublished - 1994

Fingerprint

Prilocaine
Lidocaine
Visual Analog Scale
Anesthesia
Lip
Placebos
Electrolysis
Hirsutism
Dermatologic Surgical Procedures
Pain
Local Anesthesia
Local Anesthetics
Hair
Fear
EMLA
Therapeutics

ASJC Scopus subject areas

  • Dermatology
  • Oncology

Cite this

A double-blind placebo controlled study of a 5% lidocaine/prilocaine cream (EMLA) for topical anesthesia during thermolysis. / Wagner, Richard; Flores, C. A.; Argo, L. F.

In: Journal of Dermatologic Surgery and Oncology, Vol. 20, No. 2, 1994, p. 148-150.

Research output: Contribution to journalArticle

@article{a1f7ced343a44a809b28ea15e4943341,
title = "A double-blind placebo controlled study of a 5{\%} lidocaine/prilocaine cream (EMLA) for topical anesthesia during thermolysis",
abstract = "BACKGROUND. Electrolysis and thermolysis are commonly used electrosurgical methods for the permanent destruction of unwanted hair. However, patient fear of pain during treatment may interfere with or even prevent desired treatment of hirsutism on sensitive areas such as the upper lip. OBJECTIVE. This study was conducted to assess the efficacy of EMLA (Eutectic Mixture of Local Anesthetics), a 5{\%} lidocaine/prilocaine cream, as a topically applied local anesthetic during thermolysis on the upper lip. METHODS. A double-blind placebo control study was conducted by the University of Texas Medical Branch thermolysis clinic. Thirty women with idiopathic hirsutism of the upper lip were studied. Pain was measured with a 100 mm visual analog scale (VAS). RESULTS. Total paired VAS score differences comparing the placebo VAS scores to the EMLA VAS scores were significant by paired t-test (P = .0001). Adverse reactions were mild and transient. CONCLUSION. EMLA cream may have multiple applications to the practice of dermatologic surgery, including topically achieved local anesthesia during thermolysis and electrolysis.",
author = "Richard Wagner and Flores, {C. A.} and Argo, {L. F.}",
year = "1994",
language = "English (US)",
volume = "20",
pages = "148--150",
journal = "Dermatologic Surgery",
issn = "1076-0512",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - A double-blind placebo controlled study of a 5% lidocaine/prilocaine cream (EMLA) for topical anesthesia during thermolysis

AU - Wagner, Richard

AU - Flores, C. A.

AU - Argo, L. F.

PY - 1994

Y1 - 1994

N2 - BACKGROUND. Electrolysis and thermolysis are commonly used electrosurgical methods for the permanent destruction of unwanted hair. However, patient fear of pain during treatment may interfere with or even prevent desired treatment of hirsutism on sensitive areas such as the upper lip. OBJECTIVE. This study was conducted to assess the efficacy of EMLA (Eutectic Mixture of Local Anesthetics), a 5% lidocaine/prilocaine cream, as a topically applied local anesthetic during thermolysis on the upper lip. METHODS. A double-blind placebo control study was conducted by the University of Texas Medical Branch thermolysis clinic. Thirty women with idiopathic hirsutism of the upper lip were studied. Pain was measured with a 100 mm visual analog scale (VAS). RESULTS. Total paired VAS score differences comparing the placebo VAS scores to the EMLA VAS scores were significant by paired t-test (P = .0001). Adverse reactions were mild and transient. CONCLUSION. EMLA cream may have multiple applications to the practice of dermatologic surgery, including topically achieved local anesthesia during thermolysis and electrolysis.

AB - BACKGROUND. Electrolysis and thermolysis are commonly used electrosurgical methods for the permanent destruction of unwanted hair. However, patient fear of pain during treatment may interfere with or even prevent desired treatment of hirsutism on sensitive areas such as the upper lip. OBJECTIVE. This study was conducted to assess the efficacy of EMLA (Eutectic Mixture of Local Anesthetics), a 5% lidocaine/prilocaine cream, as a topically applied local anesthetic during thermolysis on the upper lip. METHODS. A double-blind placebo control study was conducted by the University of Texas Medical Branch thermolysis clinic. Thirty women with idiopathic hirsutism of the upper lip were studied. Pain was measured with a 100 mm visual analog scale (VAS). RESULTS. Total paired VAS score differences comparing the placebo VAS scores to the EMLA VAS scores were significant by paired t-test (P = .0001). Adverse reactions were mild and transient. CONCLUSION. EMLA cream may have multiple applications to the practice of dermatologic surgery, including topically achieved local anesthesia during thermolysis and electrolysis.

UR - http://www.scopus.com/inward/record.url?scp=0028360121&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028360121&partnerID=8YFLogxK

M3 - Article

C2 - 8113509

AN - SCOPUS:0028360121

VL - 20

SP - 148

EP - 150

JO - Dermatologic Surgery

JF - Dermatologic Surgery

SN - 1076-0512

IS - 2

ER -