A minor groove binding track in reverse transcriptase

K. Bebenek; W. A. Beard; T. A. Darden; L. Li; R. Prasad; B. A. Luxon; D. G. Gorenstein; S. H. Wilson; T. A. Kunkel

doi:10.1038/nsb0397-194

A minor groove binding track in reverse transcriptase

K. Bebenek, W. A. Beard, T. A. Darden, L. Li, R. Prasad, B. A. Luxon, D. G. Gorenstein, S. H. Wilson, T. A. Kunkel

Research output: Contribution to journal › Article › peer-review

114 Scopus citations

Abstract

Evidence is presented indicating that processive synthesis by HIV-1 reverse transcriptase involves interactions between the minor groove of the template-primer and a discrete protein structural element, the minor groove binding track (MGBT).

Original language	English (US)
Pages (from-to)	194-197
Number of pages	4
Journal	Nature Structural Biology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1038/nsb0397-194
State	Published - 1997
Externally published	Yes

ASJC Scopus subject areas

Structural Biology
Biochemistry
Genetics

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title = "A minor groove binding track in reverse transcriptase",

abstract = "Evidence is presented indicating that processive synthesis by HIV-1 reverse transcriptase involves interactions between the minor groove of the template-primer and a discrete protein structural element, the minor groove binding track (MGBT).",

author = "K. Bebenek and Beard, {W. A.} and Darden, {T. A.} and L. Li and R. Prasad and Luxon, {B. A.} and Gorenstein, {D. G.} and Wilson, {S. H.} and Kunkel, {T. A.}",

year = "1997",

doi = "10.1038/nsb0397-194",

language = "English (US)",

volume = "4",

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journal = "Nature Structural Biology",

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T1 - A minor groove binding track in reverse transcriptase

AU - Bebenek, K.

AU - Beard, W. A.

AU - Darden, T. A.

AU - Li, L.

AU - Prasad, R.

AU - Luxon, B. A.

AU - Gorenstein, D. G.

AU - Wilson, S. H.

AU - Kunkel, T. A.

PY - 1997

Y1 - 1997

N2 - Evidence is presented indicating that processive synthesis by HIV-1 reverse transcriptase involves interactions between the minor groove of the template-primer and a discrete protein structural element, the minor groove binding track (MGBT).

AB - Evidence is presented indicating that processive synthesis by HIV-1 reverse transcriptase involves interactions between the minor groove of the template-primer and a discrete protein structural element, the minor groove binding track (MGBT).

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U2 - 10.1038/nsb0397-194

DO - 10.1038/nsb0397-194

M3 - Article

C2 - 9164459

AN - SCOPUS:0031039885

SN - 1072-8368

VL - 4

SP - 194

EP - 197

JO - Nature Structural Biology

JF - Nature Structural Biology

IS - 3

ER -

A minor groove binding track in reverse transcriptase

Abstract

ASJC Scopus subject areas

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