A minor groove binding track in reverse transcriptase

K. Bebenek; W. A. Beard; T. A. Darden; L. Li; R. Prasad; B. A. Luxon; D. G. Gorenstein; S. H. Wilson; T. A. Kunkel

doi:10.1038/nsb0397-194

A minor groove binding track in reverse transcriptase

K. Bebenek
, W. A. Beard
, T. A. Darden
, L. Li
, R. Prasad
, B. A. Luxon
, D. G. Gorenstein
, S. H. Wilson
, T. A. Kunkel

Research output: Contribution to journal › Article › peer-review

116 Scopus citations

Abstract

Evidence is presented indicating that processive synthesis by HIV-1 reverse transcriptase involves interactions between the minor groove of the template-primer and a discrete protein structural element, the minor groove binding track (MGBT).

Original language	English (US)
Pages (from-to)	194-197
Number of pages	4
Journal	Nature Structural Biology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1038/nsb0397-194
State	Published - 1997
Externally published	Yes

ASJC Scopus subject areas

Structural Biology
Biochemistry
Genetics

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10.1038/nsb0397-194

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@article{44eb4c71f9624289a0cdb80eb48919a3,

title = "A minor groove binding track in reverse transcriptase",

abstract = "Evidence is presented indicating that processive synthesis by HIV-1 reverse transcriptase involves interactions between the minor groove of the template-primer and a discrete protein structural element, the minor groove binding track (MGBT).",

author = "K. Bebenek and Beard, \{W. A.\} and Darden, \{T. A.\} and L. Li and R. Prasad and Luxon, \{B. A.\} and Gorenstein, \{D. G.\} and Wilson, \{S. H.\} and Kunkel, \{T. A.\}",

year = "1997",

doi = "10.1038/nsb0397-194",

language = "English (US)",

volume = "4",

pages = "194--197",

journal = "Nature Structural Biology",

issn = "1072-8368",

publisher = "Nature Research",

number = "3",

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T1 - A minor groove binding track in reverse transcriptase

AU - Bebenek, K.

AU - Beard, W. A.

AU - Darden, T. A.

AU - Li, L.

AU - Prasad, R.

AU - Luxon, B. A.

AU - Gorenstein, D. G.

AU - Wilson, S. H.

AU - Kunkel, T. A.

PY - 1997

Y1 - 1997

N2 - Evidence is presented indicating that processive synthesis by HIV-1 reverse transcriptase involves interactions between the minor groove of the template-primer and a discrete protein structural element, the minor groove binding track (MGBT).

AB - Evidence is presented indicating that processive synthesis by HIV-1 reverse transcriptase involves interactions between the minor groove of the template-primer and a discrete protein structural element, the minor groove binding track (MGBT).

UR - https://www.scopus.com/pages/publications/0031039885

UR - https://www.scopus.com/pages/publications/0031039885#tab=citedBy

U2 - 10.1038/nsb0397-194

DO - 10.1038/nsb0397-194

M3 - Article

C2 - 9164459

AN - SCOPUS:0031039885

SN - 1072-8368

VL - 4

SP - 194

EP - 197

JO - Nature Structural Biology

JF - Nature Structural Biology

IS - 3

ER -

A minor groove binding track in reverse transcriptase

Abstract

ASJC Scopus subject areas

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