A new in vivo assay of human lymphocyte-mediated immunity to melanoma

Raymond E. Richmond, Courtney M. Townsend, Donald L. Morton

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Lymphocytes from melanoma patients more frequently inhibited the growth of human melanoma cells in the hamster cheek pouch than did lymphocytes from normal donors. Growth inhibition was accomplished with a much lower ratio of target cells to lymphocytes than in in vitro assays. The hamster cheek pouch assay can be used to study the relationship of blocking factors and humoral antibodies to cell-mediated immunity against human cancers.

Original languageEnglish (US)
Pages (from-to)345-350
Number of pages6
JournalSurgery
Volume81
Issue number3
StatePublished - Mar 1977
Externally publishedYes

ASJC Scopus subject areas

  • Surgery

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