A novel handheld device for use in remote patient monitoring of heart failure patients-design and preliminary validation on healthy subjects

Luca Pollonini, Nithin O. Rajan, Shuai Xu, Sridhar Madala, Clifford C. Dacso

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Remote patient monitoring (RPM) holds great promise for reducing the burden of congestive heart failure (CHF). Improved sensor technology and effective predictive algorithms can anticipate sudden decompensation events. Enhanced telemonitoring systems would promote patient independence and facilitate communication between patients and their physicians. We report the development of a novel hand-held device, called Blue Box, capable of collecting and wirelessly transmitting key cardiac parameters derived from three integrated biosensors: 2 lead electrocardiogram (ECG), photoplethysmography and bioelectrical impedance (bioimpedance). Blue Box measurements include time intervals between consecutive ECG R-waves (RR interval), time duration of the ECG complex formed by the Q, R and S waves (QRS duration), bioimpedance, heart rate and systolic time intervals. In this study, we recruited 24 healthy subjects to collect several parameters measured by Blue Box and assess their value in correlating with cardiac output measured with Echo-Doppler. Linear correlation between the heart rate measured with Blue Box and cardiac output from Echo- Doppler had a group average correlation coefficient of 0.80. We found that systolic time intervals did not improve the model significantly. However, STIs did inversely correlate with increasing workloads.

Original languageEnglish (US)
Pages (from-to)653-659
Number of pages7
JournalJournal of Medical Systems
Volume36
Issue number2
DOIs
StatePublished - Apr 2012
Externally publishedYes

Fingerprint

Remote patient monitoring
Physiologic Monitoring
Electrocardiography
Healthy Volunteers
Acoustic impedance
Heart Failure
Systole
Electric Impedance
Cardiac Output
Equipment and Supplies
Heart Rate
Photoplethysmography
Biosensing Techniques
Sexually Transmitted Diseases
Workload
Time measurement
Biosensors
Hand
Lead
Communication

Keywords

  • Cardiac output
  • Congestive heart failure
  • Electrocardiography
  • Photoplethysmography
  • Remote patient monitoring
  • Systolic time intervals

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Health Informatics
  • Health Information Management
  • Information Systems

Cite this

A novel handheld device for use in remote patient monitoring of heart failure patients-design and preliminary validation on healthy subjects. / Pollonini, Luca; Rajan, Nithin O.; Xu, Shuai; Madala, Sridhar; Dacso, Clifford C.

In: Journal of Medical Systems, Vol. 36, No. 2, 04.2012, p. 653-659.

Research output: Contribution to journalArticle

Pollonini, Luca ; Rajan, Nithin O. ; Xu, Shuai ; Madala, Sridhar ; Dacso, Clifford C. / A novel handheld device for use in remote patient monitoring of heart failure patients-design and preliminary validation on healthy subjects. In: Journal of Medical Systems. 2012 ; Vol. 36, No. 2. pp. 653-659.
@article{77befdaab8e9408ba85c3bac9817cfe7,
title = "A novel handheld device for use in remote patient monitoring of heart failure patients-design and preliminary validation on healthy subjects",
abstract = "Remote patient monitoring (RPM) holds great promise for reducing the burden of congestive heart failure (CHF). Improved sensor technology and effective predictive algorithms can anticipate sudden decompensation events. Enhanced telemonitoring systems would promote patient independence and facilitate communication between patients and their physicians. We report the development of a novel hand-held device, called Blue Box, capable of collecting and wirelessly transmitting key cardiac parameters derived from three integrated biosensors: 2 lead electrocardiogram (ECG), photoplethysmography and bioelectrical impedance (bioimpedance). Blue Box measurements include time intervals between consecutive ECG R-waves (RR interval), time duration of the ECG complex formed by the Q, R and S waves (QRS duration), bioimpedance, heart rate and systolic time intervals. In this study, we recruited 24 healthy subjects to collect several parameters measured by Blue Box and assess their value in correlating with cardiac output measured with Echo-Doppler. Linear correlation between the heart rate measured with Blue Box and cardiac output from Echo- Doppler had a group average correlation coefficient of 0.80. We found that systolic time intervals did not improve the model significantly. However, STIs did inversely correlate with increasing workloads.",
keywords = "Cardiac output, Congestive heart failure, Electrocardiography, Photoplethysmography, Remote patient monitoring, Systolic time intervals",
author = "Luca Pollonini and Rajan, {Nithin O.} and Shuai Xu and Sridhar Madala and Dacso, {Clifford C.}",
year = "2012",
month = "4",
doi = "10.1007/s10916-010-9531-y",
language = "English (US)",
volume = "36",
pages = "653--659",
journal = "Journal of Medical Systems",
issn = "0148-5598",
publisher = "Springer New York",
number = "2",

}

TY - JOUR

T1 - A novel handheld device for use in remote patient monitoring of heart failure patients-design and preliminary validation on healthy subjects

AU - Pollonini, Luca

AU - Rajan, Nithin O.

AU - Xu, Shuai

AU - Madala, Sridhar

AU - Dacso, Clifford C.

PY - 2012/4

Y1 - 2012/4

N2 - Remote patient monitoring (RPM) holds great promise for reducing the burden of congestive heart failure (CHF). Improved sensor technology and effective predictive algorithms can anticipate sudden decompensation events. Enhanced telemonitoring systems would promote patient independence and facilitate communication between patients and their physicians. We report the development of a novel hand-held device, called Blue Box, capable of collecting and wirelessly transmitting key cardiac parameters derived from three integrated biosensors: 2 lead electrocardiogram (ECG), photoplethysmography and bioelectrical impedance (bioimpedance). Blue Box measurements include time intervals between consecutive ECG R-waves (RR interval), time duration of the ECG complex formed by the Q, R and S waves (QRS duration), bioimpedance, heart rate and systolic time intervals. In this study, we recruited 24 healthy subjects to collect several parameters measured by Blue Box and assess their value in correlating with cardiac output measured with Echo-Doppler. Linear correlation between the heart rate measured with Blue Box and cardiac output from Echo- Doppler had a group average correlation coefficient of 0.80. We found that systolic time intervals did not improve the model significantly. However, STIs did inversely correlate with increasing workloads.

AB - Remote patient monitoring (RPM) holds great promise for reducing the burden of congestive heart failure (CHF). Improved sensor technology and effective predictive algorithms can anticipate sudden decompensation events. Enhanced telemonitoring systems would promote patient independence and facilitate communication between patients and their physicians. We report the development of a novel hand-held device, called Blue Box, capable of collecting and wirelessly transmitting key cardiac parameters derived from three integrated biosensors: 2 lead electrocardiogram (ECG), photoplethysmography and bioelectrical impedance (bioimpedance). Blue Box measurements include time intervals between consecutive ECG R-waves (RR interval), time duration of the ECG complex formed by the Q, R and S waves (QRS duration), bioimpedance, heart rate and systolic time intervals. In this study, we recruited 24 healthy subjects to collect several parameters measured by Blue Box and assess their value in correlating with cardiac output measured with Echo-Doppler. Linear correlation between the heart rate measured with Blue Box and cardiac output from Echo- Doppler had a group average correlation coefficient of 0.80. We found that systolic time intervals did not improve the model significantly. However, STIs did inversely correlate with increasing workloads.

KW - Cardiac output

KW - Congestive heart failure

KW - Electrocardiography

KW - Photoplethysmography

KW - Remote patient monitoring

KW - Systolic time intervals

UR - http://www.scopus.com/inward/record.url?scp=84863187766&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863187766&partnerID=8YFLogxK

U2 - 10.1007/s10916-010-9531-y

DO - 10.1007/s10916-010-9531-y

M3 - Article

C2 - 20703666

AN - SCOPUS:84863187766

VL - 36

SP - 653

EP - 659

JO - Journal of Medical Systems

JF - Journal of Medical Systems

SN - 0148-5598

IS - 2

ER -