A novel mosquito-borne Orbivirus species found in South-east Asia

Amit Kapoor, Robert B. Tesh, Raja Duraisamy, Vsevolod Popov, Amelia P A Travassos da Rosa, W. Ian Lipkin

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The genus Orbivirus of the family Reoviridae includes a genetically diverse group of dsRNA arthropod-borne viruses that infect a wide variety of animal species. Here, we report the complete genome and phylogenetic analysis of a novel orbivirus (IAn-66411 or Sathuvachari virus, SVIV) isolated in 1963 from starlings (Brahminy myna) collected in Vellore, Tamil Nadu, India. Comparative genetic analysis of the SVIV polymerase (VP1 protein), core protein (VP3) and outer core protein (VP7) confirmed that SVIV is most closely related to the mosquito-borne orbiviruses, but that it is equally divergent from all known species. Therefore, SVIV should be tentatively considered as the prototype of a novel mosquito-associated Orbivirus species. These findings will aid in the development of molecular reagents that can identify genetically similar orbiviruses and help elucidate their geographical distribution, epidemiology, species tropism and possible disease association.

Original languageEnglish (US)
Pages (from-to)1051-1057
Number of pages7
JournalJournal of General Virology
Volume94
Issue numberPART 5
DOIs
StatePublished - May 2013

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Orbivirus
Far East
Culicidae
Viruses
Reoviridae
Arboviruses
Starlings
Proteins
Tropism
India
Epidemiology
Genome

ASJC Scopus subject areas

  • Virology

Cite this

Kapoor, A., Tesh, R. B., Duraisamy, R., Popov, V., da Rosa, A. P. A. T., & Lipkin, W. I. (2013). A novel mosquito-borne Orbivirus species found in South-east Asia. Journal of General Virology, 94(PART 5), 1051-1057. https://doi.org/10.1099/vir.0.046748-0

A novel mosquito-borne Orbivirus species found in South-east Asia. / Kapoor, Amit; Tesh, Robert B.; Duraisamy, Raja; Popov, Vsevolod; da Rosa, Amelia P A Travassos; Lipkin, W. Ian.

In: Journal of General Virology, Vol. 94, No. PART 5, 05.2013, p. 1051-1057.

Research output: Contribution to journalArticle

Kapoor, A, Tesh, RB, Duraisamy, R, Popov, V, da Rosa, APAT & Lipkin, WI 2013, 'A novel mosquito-borne Orbivirus species found in South-east Asia', Journal of General Virology, vol. 94, no. PART 5, pp. 1051-1057. https://doi.org/10.1099/vir.0.046748-0
Kapoor, Amit ; Tesh, Robert B. ; Duraisamy, Raja ; Popov, Vsevolod ; da Rosa, Amelia P A Travassos ; Lipkin, W. Ian. / A novel mosquito-borne Orbivirus species found in South-east Asia. In: Journal of General Virology. 2013 ; Vol. 94, No. PART 5. pp. 1051-1057.
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