A novel mosquito-borne Orbivirus species found in South-east Asia

Amit Kapoor, Robert B. Tesh, Raja Duraisamy, Vsevolod L. Popov, Amelia P.A.Travassos da Rosa, W. Ian Lipkin

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15 Scopus citations

Abstract

The genus Orbivirus of the family Reoviridae includes a genetically diverse group of dsRNA arthropod-borne viruses that infect a wide variety of animal species. Here, we report the complete genome and phylogenetic analysis of a novel orbivirus (IAn-66411 or Sathuvachari virus, SVIV) isolated in 1963 from starlings (Brahminy myna) collected in Vellore, Tamil Nadu, India. Comparative genetic analysis of the SVIV polymerase (VP1 protein), core protein (VP3) and outer core protein (VP7) confirmed that SVIV is most closely related to the mosquito-borne orbiviruses, but that it is equally divergent from all known species. Therefore, SVIV should be tentatively considered as the prototype of a novel mosquito-associated Orbivirus species. These findings will aid in the development of molecular reagents that can identify genetically similar orbiviruses and help elucidate their geographical distribution, epidemiology, species tropism and possible disease association.

Original languageEnglish (US)
Pages (from-to)1051-1057
Number of pages7
JournalJournal of General Virology
Volume94
Issue numberPART 5
DOIs
StatePublished - May 1 2013

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ASJC Scopus subject areas

  • Virology

Cite this

Kapoor, A., Tesh, R. B., Duraisamy, R., Popov, V. L., da Rosa, A. P. A. T., & Lipkin, W. I. (2013). A novel mosquito-borne Orbivirus species found in South-east Asia. Journal of General Virology, 94(PART 5), 1051-1057. https://doi.org/10.1099/vir.0.046748-0