A novel SCN5A mutation V1340I in Brugada syndrome augmenting arrhythmias during febrile illness

Keyphrases

• Arrhythmia 100%
• Background mutations 16%
• Brugada Syndrome 100%
• Cardiac Sodium Channel 16%
• Current Density 16%
• Fast Inactivation 16%
• Febrile Illness 100%
• Fever 33%
• Frequent Episodes 16%
• HNav1.5 16%
• Hyperthermia 16%
• Immunohistochemical Staining 16%
• Loss Function 16%
• Missense mutation 16%
• Patch-clamp Technique 16%
• Pathophysiological Mechanisms 16%
• Peak Current Density 16%
• Plasma Membrane 16%
• Polymorphic Ventricular Tachycardia 16%
• Recovery Time 16%
• SCN5A 100%
• SCN5A Gene 16%
• SCN5A mutation 100%
• Sodium Current 33%
• Splice Variant 16%
• Steady State 16%
• Study Support 16%
• Syncope 16%
• Ventricular Arrhythmia 16%
• Voltage Dependence 16%

Biochemistry, Genetics and Molecular Biology

• Brugada Syndrome 100%
• Cardiac Dysrhythmia 100%
• Cell Membrane 20%
• Current Density 40%
• Electric Potential 20%
• Missense Mutation 20%
• Patch Clamp 20%
• Sodium Channel 20%
• Sodium Current 40%
• Steady State 20%
• Ventricular Tachycardia 20%
• Wild Type 100%