A novel vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis

José M C Ribeiro, André Vachereau, Govind B. Modi, Robert B. Tesh

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

Salivary gland lysates of the sand fly Lutzomyia longipalpis contain a potent vasodilator that aids the fly to feed on the blood of its vertebrate hosts. Chromatographic analysis, antibody reactivity, and data obtained from bioassays of the salivary erythema-inducing factor indicate striking similarity with human calcitonin gene-related peptide. The erythema-inducing factor is, however, at least one order of magnitude more potent than calcitonin gene-related peptide.

Original languageEnglish (US)
Pages (from-to)212-214
Number of pages3
JournalScience
Volume243
Issue number4888
StatePublished - 1989
Externally publishedYes

Fingerprint

Psychodidae
Calcitonin Gene-Related Peptide
Erythema
Salivary Glands
Peptides
Vasodilator Agents
Diptera
Biological Assay
Vertebrates
Chromatography
Antibodies

ASJC Scopus subject areas

  • General

Cite this

Ribeiro, J. M. C., Vachereau, A., Modi, G. B., & Tesh, R. B. (1989). A novel vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis. Science, 243(4888), 212-214.

A novel vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis. / Ribeiro, José M C; Vachereau, André; Modi, Govind B.; Tesh, Robert B.

In: Science, Vol. 243, No. 4888, 1989, p. 212-214.

Research output: Contribution to journalArticle

Ribeiro, JMC, Vachereau, A, Modi, GB & Tesh, RB 1989, 'A novel vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis', Science, vol. 243, no. 4888, pp. 212-214.
Ribeiro JMC, Vachereau A, Modi GB, Tesh RB. A novel vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis. Science. 1989;243(4888):212-214.
Ribeiro, José M C ; Vachereau, André ; Modi, Govind B. ; Tesh, Robert B. / A novel vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis. In: Science. 1989 ; Vol. 243, No. 4888. pp. 212-214.
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