A randomized controlled study of two educational interventions on adherence with oral contraceptives and condoms

Abbey B. Berenson, Mahbubur Rahman

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


Background: The study was conducted to examine the effectiveness of two different interventions on oral contraception (OC) adherence and condom use. Study Design: A total of 1,155 women 16-24 years of age requesting OC were randomized to receive either face-to-face behavioral counseling and education at their baseline clinic visit (C group; n= 383) or this same intervention followed by monthly phone calls for 6 months (C+P group; n= 384) or standard care (S group; n= 388). Phone interviews at 3, 6 and 12 months after the initial visit as well as a medical record review assessed OC continuation, condom use and several other secondary and clinically meaningful outcomes such as pregnancy and sexually transmitted infection (STI) rates and correct use of pills. Results: The interventions did not have a significant effect on OC continuation after 3 (C+P: 58%; C: 50%; S: 55%), 6 (39%; 32%; 37%) or 12 months (20%; 18%; 20%) (p>.05). Condom use at last sexual intercourse did not differ by intervention methods (p>.05). Moreover, no effect was observed on pregnancy [S=48 (12.4%), C = 63 (16.5%), C+P=52 (13.5%); p=.22] and STI [S=18 (4.6%), C=12 (3.1%), C+P=13 (3.4%); p=.50] rates, and mean number of correctly used pill packs (p=.06). However, those randomized to C+P were more likely than C and S patients to identify a cue and report that the cue worked as a reminder to take their OC on time based on 3 and 6 months follow-up information (p<.01 for all relationships). Conclusions: Neither intervention in this study improved OC adherence among young women.

Original languageEnglish (US)
Pages (from-to)716-724
Number of pages9
Issue number6
StatePublished - Dec 2012


  • Adherence
  • Condom
  • Educational Interventions
  • Oral contraception
  • Randomized Controlled Trial
  • Young Adult Women

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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