A randomized pilot clinical trial of pravastatin versus placebo in pregnant patients at high risk of preeclampsia

Keyphrases

• Preeclampsia 100%
• Placebo 100%
• High Risk 100%
• Pregnant Women 100%
• Atorvastatin 100%
• Pilot Randomized Controlled Trial 100%
• During Pregnancy 16%
• Pharmacokinetic Parameters 16%
• Pregnancy Outcome 11%
• Neonatal Outcome 11%
• Umbilical Cord Blood 11%
• Area under the Curve 11%
• Preeclampsia Prevention 11%
• Blood Biochemistry 11%
• Oral Clearance 11%
• Maximum Permissible Concentration 11%
• Safety Parameters 11%
• Clinical Trials 5%
• Pharmacokinetics 5%
• Pharmacokinetic Study 5%
• Third Trimester 5%
• Non-pregnant Women 5%
• Steady State 5%
• Delivery Time 5%
• Phase I Clinical Trial 5%
• Maternal Outcomes 5%
• Week of Gestation 5%
• Dose Rate 5%
• Drug Exposure 5%
• High-risk Women 5%
• Neonatal Morbidity 5%
• Neonatal Mortality 5%
• Maternal-fetal 5%
• Maternal Morbidity 5%
• No Significant Difference 5%
• Serious Adverse Events 5%
• Birth Weight 5%
• Headache 5%
• Randomized Trial 5%
• Preterm Delivery 5%
• Postpartum Period 5%
• Umbilical Cord 5%
• Limit of Quantification 5%
• Singleton 5%
• Congenital Anomalies 5%
• Risk-benefit Analysis 5%
• Dose-independent 5%
• Gestational Age at Delivery 5%
• High-risk Pregnant Women 5%
• Fetal Safety 5%
• Biological Plausibility 5%
• Second Trimester of Pregnancy 5%
• Auditory Brainstem Response 5%
• Favorable Risk 5%
• Placebo-controlled Randomized Trial 5%
• Heartburn 5%
• Overall Safety 5%
• Musculoskeletal Pain 5%
• Total Drug 5%
• Maximal Area 5%
• Evoked Response Potential 5%
• Hearing Screening Test 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Clinical Trial 100%
• Placebo 100%
• Preeclampsia 100%
• Pravastatin 100%
• Pharmacokinetic Parameter 16%
• Pharmacokinetics 11%
• Adverse Event 5%
• Side Effect 5%
• Newborn Morbidity 5%
• Newborn Mortality 5%
• Premature Labor 5%
• Maternal Morbidity 5%
• Randomized Controlled Trial 5%
• Headache 5%
• Congenital Malformation 5%
• Heartburn 5%
• Musculoskeletal Pain 5%