Abstract
Acute kidney injury (AKI) in patients with coronavirus disease 2019 (COVID-19) is common, especially among severely ill patients. While acute tubular necrosis (ATN) is one of the most common findings in published kidney biopsy series for patients with COVID-19 infections, a number of glomerular pathologies have been described as well. Among glomerular pathologies in COVID-19, COVID-19-Associated Collapsing Glomerulopathy (COVAN) remains the most common pattern of injury. Patients with 2 high-risk APOL1 alleles appear to be at increased risk for COVAN, similar to other forms of collapsing glomerulopathy such as HIV-Associated Nephropathy. Acute interstitial nephritis (AIN) is a less common finding in patients with COVID-19 and reported cases have been mild. Reports of a subtype of AIN, granulomatous interstitial nephritis (GIN), among COVID-19 patients are extremely rare and have not been reported in association with COVAN. Here, we report a case of COVAN associated with severe GIN.
Original language | English (US) |
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Journal | Journal of Investigative Medicine High Impact Case Reports |
Volume | 10 |
DOIs | |
State | Published - 2022 |
Externally published | Yes |
Keywords
- AIN
- AKI
- COVAN
- COVID-19
- GIN
- nephrology
ASJC Scopus subject areas
- Epidemiology
- Safety, Risk, Reliability and Quality
- Safety Research