Abstract
Extraskeletal osteosarcoma (ESOS) is a rare variant of osteosarcoma that arises without attachment to the underlying skeleton. These cancers are typically found embedded in deeper tissues, most commonly the muscle or fascia, and are rarely found within the skin or subcutis. Most tumors are large in size upon initial presentation, and carry a poor prognosis. We discuss the case of a 48-year-old Caucasian woman who presented to a dermatology clinic with an asymptomatic, small, mobile, subcutaneous mass that appeared clinically benign. After elective removal and histopathologic examination, the patient was diagnosed with ESOS. ESOS presenting in this manner is exceedingly rare, and this case highlights the importance of sending all excised specimens, even those with a benign presentation, for pathologic examination.
| Original language | English (US) |
|---|---|
| Journal | Journal of Cutaneous Pathology |
| DOIs | |
| State | Published - Jan 1 2019 |
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Keywords
- dermatology
- extraskeletal osteosarcoma
- neoplasm
- pathology
- skin
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology
- Dermatology
Cite this
A rare variant of extraskeletal osteosarcoma presenting as a clinically benign subcutaneous neoplasm. / Ryan, Michael P.; Woolridge, Katelyn F.; Sedrak, Michael; Berlingeri-Ramos, Alma C.; Group, Ashley.
In: Journal of Cutaneous Pathology, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A rare variant of extraskeletal osteosarcoma presenting as a clinically benign subcutaneous neoplasm
AU - Ryan, Michael P.
AU - Woolridge, Katelyn F.
AU - Sedrak, Michael
AU - Berlingeri-Ramos, Alma C.
AU - Group, Ashley
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Extraskeletal osteosarcoma (ESOS) is a rare variant of osteosarcoma that arises without attachment to the underlying skeleton. These cancers are typically found embedded in deeper tissues, most commonly the muscle or fascia, and are rarely found within the skin or subcutis. Most tumors are large in size upon initial presentation, and carry a poor prognosis. We discuss the case of a 48-year-old Caucasian woman who presented to a dermatology clinic with an asymptomatic, small, mobile, subcutaneous mass that appeared clinically benign. After elective removal and histopathologic examination, the patient was diagnosed with ESOS. ESOS presenting in this manner is exceedingly rare, and this case highlights the importance of sending all excised specimens, even those with a benign presentation, for pathologic examination.
AB - Extraskeletal osteosarcoma (ESOS) is a rare variant of osteosarcoma that arises without attachment to the underlying skeleton. These cancers are typically found embedded in deeper tissues, most commonly the muscle or fascia, and are rarely found within the skin or subcutis. Most tumors are large in size upon initial presentation, and carry a poor prognosis. We discuss the case of a 48-year-old Caucasian woman who presented to a dermatology clinic with an asymptomatic, small, mobile, subcutaneous mass that appeared clinically benign. After elective removal and histopathologic examination, the patient was diagnosed with ESOS. ESOS presenting in this manner is exceedingly rare, and this case highlights the importance of sending all excised specimens, even those with a benign presentation, for pathologic examination.
KW - dermatology
KW - extraskeletal osteosarcoma
KW - neoplasm
KW - pathology
KW - skin
UR - http://www.scopus.com/inward/record.url?scp=85065258818&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85065258818&partnerID=8YFLogxK
U2 - 10.1111/cup.13474
DO - 10.1111/cup.13474
M3 - Article
JO - Journal of Cutaneous Pathology
JF - Journal of Cutaneous Pathology
SN - 0303-6987
ER -