A self-adjuvanting supramolecular vaccine carrying a folded protein antigen

Gregory A. Hudalla; Justin A. Modica; Ye F. Tian; Jai S. Rudra; Anita S. Chong; Tao Sun; Milan Mrksich; Joel H. Collier

doi:10.1002/adhm.201200435

A self-adjuvanting supramolecular vaccine carrying a folded protein antigen

Gregory A. Hudalla, Justin A. Modica, Ye F. Tian, Jai S. Rudra, Anita S. Chong, Tao Sun, Milan Mrksich, Joel H. Collier

Research output: Contribution to journal › Article › peer-review

93 Scopus citations

Abstract

This work illustrates a strategy for the design of molecularly defined immunotherapies, using a blend of supramolecular peptide self-assembly and active site-directed protein capture.

Original language	English (US)
Pages (from-to)	1114-1119
Number of pages	6
Journal	Advanced Healthcare Materials
Volume	2
Issue number	8
DOIs	https://doi.org/10.1002/adhm.201200435
State	Published - Aug 2013
Externally published	Yes

Keywords

Biomolecular materials
Immunotherapy
Nanofibers
Proteins
Self-assembly

ASJC Scopus subject areas

Biomaterials
Biomedical Engineering
Pharmaceutical Science

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10.1002/adhm.201200435

Cite this

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title = "A self-adjuvanting supramolecular vaccine carrying a folded protein antigen",

abstract = "This work illustrates a strategy for the design of molecularly defined immunotherapies, using a blend of supramolecular peptide self-assembly and active site-directed protein capture.",

keywords = "Biomolecular materials, Immunotherapy, Nanofibers, Proteins, Self-assembly",

author = "Hudalla, {Gregory A.} and Modica, {Justin A.} and Tian, {Ye F.} and Rudra, {Jai S.} and Chong, {Anita S.} and Tao Sun and Milan Mrksich and Collier, {Joel H.}",

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AU - Modica, Justin A.

AU - Tian, Ye F.

AU - Rudra, Jai S.

AU - Chong, Anita S.

AU - Sun, Tao

AU - Mrksich, Milan

AU - Collier, Joel H.

PY - 2013/8

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KW - Immunotherapy

KW - Nanofibers

KW - Proteins

KW - Self-assembly

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A self-adjuvanting supramolecular vaccine carrying a folded protein antigen

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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