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A survey for antibodies to Lassa virus among health workers in Nigeria

  • M. D. Bajani
  • , O. Tomori
  • , P. E. Rollin
  • , T. O. Harry
  • , N. D. Bukbuk
  • , L. Wilson
  • , J. E. Childs
  • , C. J. Peters
  • , T. G. Ksiazek

Research output: Contribution to journalArticlepeer-review

Abstract

A study was conducted among 552 health workers at 6 health facilities in Nigeria. Lassa virus immunoglobulin (Ig) G antibody was detected in 12.3%, using an enzyme-linked immunosorbent assay. Antibody prevalence in the 6 health centres ranged from 1.2% to 27.3%. Prevalences were higher in primary and secondary health facilities than in tertiary centres. Seroprevalences ranged from 1.7% to 23.7% among different occupational groups of health workers; the highest observed antibody prevalence was among ward aids. Lassa virus IgM antibody, indicating recent infection, was present in 6 of the health workers, 5 of whom were ward aids and one was a nurse. All of the health workers with specific IgM came from a single facility in Lafia, sampled during an outbreak of Lassa fever.

Original languageEnglish (US)
Pages (from-to)379-381
Number of pages3
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume91
Issue number4
DOIs
StatePublished - 1997
Externally publishedYes

Keywords

  • Health workers
  • Lassa fever
  • Nigeria
  • Seroprevalence

ASJC Scopus subject areas

  • Parasitology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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