A survey of hantavirus antibody in small-mammal populations in selected United States National Parks

James N. Mills, Jerry M. Johnson, Thomas Ksiazek, Barbara A. Ellis, Pierre E. Rollin, Terry L. Yates, Michael O. Mann, Mark R. Johnson, Mariel L. Campbell, Jennifer Miyashiro, Michael Patrick, Michael Zyzak, Dave Lavender, Mark G. Novak, Karina Schmidt, C. J. Peters, James E. Childs

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

Hantavirus activity in 39 National Parks in the eastern and central United States was surveyed by testing 1,815 small mammals of 38 species for antibody reactive to Sin Nombre virus. Antibody-positive rodents were found throughout the area sampled, and in most biotic communities. Antibody was detected in 7% of 647 deer mice (Peromyscus maniculatus), 2% of 590 white- footed mice (P. leucopus), 17% of 12 rice rats (Oryzomys palustris), 3% of 31 cotton rats (Sigmodon hispidus), and 33% of 18 western harvest mice (Reithrodontomys megalotis). Antibody was also found in three of six species of voles, and in one of 33 chipmunks (Tamias minimus). Prevalence among Peromyscus was highest in the northeast. Although few cases of hantavirus pulmonary syndrome have been identified from the eastern and central regions, widespread infection in reservoir populations indicates that potential exists for human infection throughout much of the United States.

Original languageEnglish (US)
Pages (from-to)525-532
Number of pages8
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume58
Issue number4
StatePublished - 1998
Externally publishedYes

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Sigmodontinae
Peromyscus
Hantavirus
Mammals
Sciuridae
Antibodies
Population
Sin Nombre virus
Hantavirus Pulmonary Syndrome
Biota
Arvicolinae
Infection
Rodentia
Surveys and Questionnaires
Recreational Parks

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Mills, J. N., Johnson, J. M., Ksiazek, T., Ellis, B. A., Rollin, P. E., Yates, T. L., ... Childs, J. E. (1998). A survey of hantavirus antibody in small-mammal populations in selected United States National Parks. American Journal of Tropical Medicine and Hygiene, 58(4), 525-532.

A survey of hantavirus antibody in small-mammal populations in selected United States National Parks. / Mills, James N.; Johnson, Jerry M.; Ksiazek, Thomas; Ellis, Barbara A.; Rollin, Pierre E.; Yates, Terry L.; Mann, Michael O.; Johnson, Mark R.; Campbell, Mariel L.; Miyashiro, Jennifer; Patrick, Michael; Zyzak, Michael; Lavender, Dave; Novak, Mark G.; Schmidt, Karina; Peters, C. J.; Childs, James E.

In: American Journal of Tropical Medicine and Hygiene, Vol. 58, No. 4, 1998, p. 525-532.

Research output: Contribution to journalArticle

Mills, JN, Johnson, JM, Ksiazek, T, Ellis, BA, Rollin, PE, Yates, TL, Mann, MO, Johnson, MR, Campbell, ML, Miyashiro, J, Patrick, M, Zyzak, M, Lavender, D, Novak, MG, Schmidt, K, Peters, CJ & Childs, JE 1998, 'A survey of hantavirus antibody in small-mammal populations in selected United States National Parks', American Journal of Tropical Medicine and Hygiene, vol. 58, no. 4, pp. 525-532.
Mills, James N. ; Johnson, Jerry M. ; Ksiazek, Thomas ; Ellis, Barbara A. ; Rollin, Pierre E. ; Yates, Terry L. ; Mann, Michael O. ; Johnson, Mark R. ; Campbell, Mariel L. ; Miyashiro, Jennifer ; Patrick, Michael ; Zyzak, Michael ; Lavender, Dave ; Novak, Mark G. ; Schmidt, Karina ; Peters, C. J. ; Childs, James E. / A survey of hantavirus antibody in small-mammal populations in selected United States National Parks. In: American Journal of Tropical Medicine and Hygiene. 1998 ; Vol. 58, No. 4. pp. 525-532.
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