Acceleration of fetal lung maturation following prolonged rupture of the membranes

Carol Richardson, Jeffrey J. Pomerance, M. Douglas Cunningham, Louis Gluck

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Prolonged rupture of the membranes exerts an accelerating effect on fetal lung maturation independent of gestational age or birth weight and resulting in absence of the respiratory distress syndrome (RDS). Sixty-four true-premature infants born of mothers with no complications of pregnancy other than prolonged rupture of the membranes were evaluated for the presence of RDS. In 42 of these infants, membranes were ruptured 24 hours or less prior to delivery, and RDS occurred in 64 per cent. In 22 infants with membranes ruptured more than 24 hours prior to delivery, 31 per cent developed RDS. Lecithin/sphingomyelin ratios showed marked acceleration following membrane rupture, irrespective of gestational age.

Original languageEnglish
Pages (from-to)1115-1118
Number of pages4
JournalAmerican Journal of Obstetrics and Gynecology
Volume118
Issue number8
StatePublished - Apr 15 1974
Externally publishedYes

Fingerprint

Rupture
Lung
Membranes
Gestational Age
Prolonged Pregnancy
Sphingomyelins
Pregnancy Complications
Lecithins
Birth Weight
Premature Infants
Mothers

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Acceleration of fetal lung maturation following prolonged rupture of the membranes. / Richardson, Carol; Pomerance, Jeffrey J.; Cunningham, M. Douglas; Gluck, Louis.

In: American Journal of Obstetrics and Gynecology, Vol. 118, No. 8, 15.04.1974, p. 1115-1118.

Research output: Contribution to journalArticle

Richardson, Carol ; Pomerance, Jeffrey J. ; Cunningham, M. Douglas ; Gluck, Louis. / Acceleration of fetal lung maturation following prolonged rupture of the membranes. In: American Journal of Obstetrics and Gynecology. 1974 ; Vol. 118, No. 8. pp. 1115-1118.
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