TY - JOUR
T1 - Acceleration of fetal lung maturation following prolonged rupture of the membranes
AU - Richardson, C. Joan
AU - Pomerance, Jeffrey J.
AU - Cunningham, M. Douglas
AU - Gluck, Louis
N1 - Funding Information:
Supported by United States Public Health Service Research Grants Nos. HD-04380 and HD-03015, SCOR Grant No. HL-14169, National Institute of Child Health and Human Development Grant No. HD-00335, and Gerber Products Company.
PY - 1974/4/15
Y1 - 1974/4/15
N2 - Prolonged rupture of the membranes exerts an accelerating effect on fetal lung maturation independent of gestational age or birth weight and resulting in absence of the respiratory distress syndrome (RDS). Sixty-four true-premature infants born of mothers with no complications of pregnancy other than prolonged rupture of the membranes were evaluated for the presence of RDS. In 42 of these infants, membranes were ruptured 24 hours or less prior to delivery, and RDS occurred in 64 per cent. In 22 infants with membranes ruptured more than 24 hours prior to delivery, 31 per cent developed RDS. Lecithin/sphingomyelin ratios showed marked acceleration following membrane rupture, irrespective of gestational age.
AB - Prolonged rupture of the membranes exerts an accelerating effect on fetal lung maturation independent of gestational age or birth weight and resulting in absence of the respiratory distress syndrome (RDS). Sixty-four true-premature infants born of mothers with no complications of pregnancy other than prolonged rupture of the membranes were evaluated for the presence of RDS. In 42 of these infants, membranes were ruptured 24 hours or less prior to delivery, and RDS occurred in 64 per cent. In 22 infants with membranes ruptured more than 24 hours prior to delivery, 31 per cent developed RDS. Lecithin/sphingomyelin ratios showed marked acceleration following membrane rupture, irrespective of gestational age.
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U2 - 10.1016/0002-9378(74)90691-7
DO - 10.1016/0002-9378(74)90691-7
M3 - Article
C2 - 4817647
AN - SCOPUS:0016367177
SN - 0002-9378
VL - 118
SP - 1115
EP - 1118
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 8
ER -