Accuracy of magnetic resonance imaging for preoperative detection of portal vein thrombosis in liver transplant candidates

Tilak U. Shah, Richard C. Semelka, Vasilis Voultsinos, Jorge Elias, Ersan Altun, Ertan Pamuklar, Zeynep Firat, David A. Gerber, Jeffrey Fair, Mark W. Russo

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The detection of main portal vein thrombosis (PVT) on preoperative imaging of liver transplant candidates has important technical implications for the transplantation procedure. Data are scarce regarding the accuracy of magnetic resonance imaging (MRI) at detecting PVT. The aim of our study was to compare preoperative findings of the portal vein on MRI to operative findings at liver transplantation. Abdominal MRI and clinical records of 172 consecutive patients who received liver transplants between January 1999 and September 2004 were reviewed. Two radiologists independently evaluated the last abdominal magnetic resonance examinations obtained before liver transplantation, blinded to the original reading, operative findings, and clinical data. Findings on MRI were compared with intraoperative findings at transplantation. Main PVT was detected in 12 patients, in whom 8 were found to have thrombus at surgery, with 6 requiring a jump graft or thrombectomy. Sensitivity and specificity of MRI for detecting main PVT were 100% and 98%, respectively. The cause of discordance between findings on MRI and at transplantation in 2 cases was a diminutive caliber of the main portal vein that was interpreted as recanalized chronic thrombosis on MRI. In conclusion, in our study group MRI detected PVT in all liver transplant recipients requiring jump grafts at transplantation. The major reason for a false-positive MRI was a diminutive but patent portal vein.

Original languageEnglish (US)
Pages (from-to)1682-1688
Number of pages7
JournalLiver Transplantation
Volume12
Issue number11
DOIs
StatePublished - Nov 2006
Externally publishedYes

Fingerprint

Portal Vein
Thrombosis
Magnetic Resonance Imaging
Transplants
Liver
Transplantation
Liver Transplantation
Thrombectomy
Reading
Magnetic Resonance Spectroscopy
Sensitivity and Specificity

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Shah, T. U., Semelka, R. C., Voultsinos, V., Elias, J., Altun, E., Pamuklar, E., ... Russo, M. W. (2006). Accuracy of magnetic resonance imaging for preoperative detection of portal vein thrombosis in liver transplant candidates. Liver Transplantation, 12(11), 1682-1688. https://doi.org/10.1002/lt.20873

Accuracy of magnetic resonance imaging for preoperative detection of portal vein thrombosis in liver transplant candidates. / Shah, Tilak U.; Semelka, Richard C.; Voultsinos, Vasilis; Elias, Jorge; Altun, Ersan; Pamuklar, Ertan; Firat, Zeynep; Gerber, David A.; Fair, Jeffrey; Russo, Mark W.

In: Liver Transplantation, Vol. 12, No. 11, 11.2006, p. 1682-1688.

Research output: Contribution to journalArticle

Shah, TU, Semelka, RC, Voultsinos, V, Elias, J, Altun, E, Pamuklar, E, Firat, Z, Gerber, DA, Fair, J & Russo, MW 2006, 'Accuracy of magnetic resonance imaging for preoperative detection of portal vein thrombosis in liver transplant candidates', Liver Transplantation, vol. 12, no. 11, pp. 1682-1688. https://doi.org/10.1002/lt.20873
Shah, Tilak U. ; Semelka, Richard C. ; Voultsinos, Vasilis ; Elias, Jorge ; Altun, Ersan ; Pamuklar, Ertan ; Firat, Zeynep ; Gerber, David A. ; Fair, Jeffrey ; Russo, Mark W. / Accuracy of magnetic resonance imaging for preoperative detection of portal vein thrombosis in liver transplant candidates. In: Liver Transplantation. 2006 ; Vol. 12, No. 11. pp. 1682-1688.
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