Activation of protein kinase-C differentially regulates insulin-like growth factor-I and basic fibroblast growth factor messenger RNA levels

Keyphrases

• Growth Factors 100%
• Messenger RNA (mRNA) 100%
• MRNA Level 100%
• Insulin-like 100%
• Basic Fibroblast Growth Factor (bFGF) 100%
• Protein Kinase C 100%
• Phorbol 12-myristate 13-acetate 57%
• Thrombin 36%
• Bradykinin 31%
• Fibroblasts 10%
• Staurosporine 10%
• Peak Effect 10%
• Sphingosine 10%
• Dose-response Study 5%
• Differential Effects 5%
• High Dose 5%
• Cellular Events 5%
• Glycerol 5%
• Conditioned Medium 5%
• Cycloheximide 5%
• Protein Synthesis Inhibition 5%
• Incubation 5%
• RNase Protection 5%
• Acetyl 5%
• Phorbol Ester 5%
• Serum-free Medium 5%
• Pre-incubation 5%
• S6 Kinase 1 (S6K1) 5%
• Inositol Phosphate 5%
• Diacylglycerol 5%
• Dermal Fibroblasts 5%
• Tumor-promoting 5%
• Sustained Effect 5%
• Dose-dependent 5%
• Cytosol 5%

Neuroscience

• Insulin-Like Growth Factor 1 100%
• Protein Kinase C 100%
• Basic Fibroblast Growth Factor 100%
• Messenger RNA 100%
• Phorbol 57%
• Myristic Acid 52%
• Acetate 52%
• Thrombin 33%
• Bradykinin 28%
• Bovine Serum Albumin 19%
• Fibroblast 14%
• Staurosporine 9%
• Sphingosine 9%
• In Vivo 4%
• Protein Biosynthesis 4%
• Growth Factor 4%
• Ribonuclease 4%
• Cycloheximide 4%
• Diglyceride 4%
• Inositol Phosphate 4%
• S6 Kinase 4%
• Immunoreactive Insulin 4%
• Glycerol 4%