Acute intermittent porphyria presenting with posterior reversible encephalopathy syndrome and lateralized periodic discharges plus fast activity on EEG

Diosely C. Silveira, Mahrukh Bashir, Joshua Daniel, Michelle H. Lucena, Frank Bonpietro

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

We report on a 20-year-old patient with a 6-month history of recurrent abdominal pain and a 3-day history of vomiting, hypertension, seizures, and encephalopathy. The brain MRI showed posterior reversible encephalopathy syndrome, and continuous EEG (cEEG) monitoring showed lateralized periodic discharges plus fast activity. Comprehensive CSF studies were negative. Because of severe abdominal pain without a definite etiology, we requested urine porphobilinogen and serum and fecal porphyrins, which suggested acute intermittent porphyria (AIP). The patient had a complete resolution of her symptoms with carbohydrate loading and high caloric diet. Acute intermittent porphyria is potentially life-threatening without proper management and prevention of triggers if it is not recognized.

Original languageEnglish (US)
Pages (from-to)58-60
Number of pages3
JournalEpilepsy and Behavior Case Reports
Volume6
DOIs
StatePublished - 2016
Externally publishedYes

Keywords

  • LPDs
  • PRES
  • Porphyria
  • Seizures

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience

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