Acute lymphoblastic leukemia presenting with mesenteric ischemia

Timothy Krill, Michelle Baliss, Jenine Zaibaq, Hamza M. Abdulla, Sreeram Parupudi

Research output: Contribution to journalArticle

Abstract

Malignancy can induce a hypercoagulable state and lead to an increased risk of thromboembolic events. The pathogenesis of the prothrombotic state in cancer is complicated but is thought to involve several mechanisms. Thrombosis predominantly affects the venous circulation and infrequently the arteries. Arterial occlusion as an initial manifestation of acute leukemia is unusual. This is a case of a 44-year-old male admitted with complete thrombotic occlusion of the superior mesenteric artery and treated with emergent thrombectomy. Hematologic work-up was consistent with a diagnosis of T-cell acute lymphoblastic leukemia. To our knowledge, this is the first case of complete occlusion of the superior mesenteric artery presenting as the initial manifestation of T-cell acute lymphoblastic leukemia.

Original languageEnglish (US)
Pages (from-to)370-373
Number of pages4
JournalGastroenterology and Hepatology from Bed to Bench
Volume12
Issue number4
DOIs
StatePublished - Jan 1 2019

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Keywords

  • Arterial occlusion
  • Leukemia
  • Mesenteric ischemia

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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