Acute normovolemic red cell exchange for cardiopulmonary bypass in sickle cell disease

Gerald Shulman, Christopher McQuitty, Roger A. Vertrees, Vincent Conti

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A patient with sickle cell disease (hematocrit, 28.5%; hemoglobin S fraction, 79%), required mitral valve repair. Partial red cell removal and blood component sequestration with an autotransfusion device before cardiopulmonary bypass initially decreased the sickle red cell mass. This was followed by an acute one-volume whole blood exchange transfusion performed upon the initiation of cardiopulmonary bypass, resulting in a further reduction. Both techniques yielded fresh autologous plasma for use; sequestration yielded a platelet-pheresis product. Adequate postbypass hemostasis was demonstrated.

Original languageEnglish (US)
Pages (from-to)1444-1446
Number of pages3
JournalAnnals of Thoracic Surgery
Volume65
Issue number5
DOIs
StatePublished - May 1998

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Sickle Cell Anemia
Cardiopulmonary Bypass
Whole Blood Exchange Transfusion
Erythrocyte Volume
Sickle Hemoglobin
Autologous Blood Transfusions
Blood Component Removal
Hemostasis
Mitral Valve
Hematocrit
Blood Platelets
Erythrocytes
Equipment and Supplies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Acute normovolemic red cell exchange for cardiopulmonary bypass in sickle cell disease. / Shulman, Gerald; McQuitty, Christopher; Vertrees, Roger A.; Conti, Vincent.

In: Annals of Thoracic Surgery, Vol. 65, No. 5, 05.1998, p. 1444-1446.

Research output: Contribution to journalArticle

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