Adhesins of enteropathogenic Escherichia coli

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Enteropathogenic Escherichia coli (EPEC) strains induce morphological changes in infected epithelial cells. The resulting attaching and effacing (A/E) lesion is characterized by intimate bacterial adherence to epithelial cells, with microvillus destruction, cytoskeletal rearrangement, and aggregation of host cytoskeletal proteins. This review presents an overview of the adhesion mechanisms used for the colonization of the human gastrointestinal tract by EPEC. The mechanisms underlying EPEC adhesion, prior to and during the formation of the A/E lesion, and the host cytosolic responses to bacterial infection leading to diarrheal disease are discussed.

Original languageEnglish (US)
JournalEcoSal Plus
Volume2
Issue number1
DOIs
StatePublished - 2006

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Enteropathogenic Escherichia coli
Epithelial Cells
Cytoskeletal Proteins
Microvilli
Bacterial Infections
Gastrointestinal Tract

ASJC Scopus subject areas

  • Microbiology

Cite this

Adhesins of enteropathogenic Escherichia coli. / Torres, Alfredo.

In: EcoSal Plus, Vol. 2, No. 1, 2006.

Research output: Contribution to journalArticle

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