Advanced imaging for extended window stroke therapy

Jeremy J. Heit; Gregory W. Albers; Max Wintermark

doi:10.1007/978-3-031-49963-0_6

Advanced imaging for extended window stroke therapy

Jeremy J. Heit
, Gregory W. Albers
, Max Wintermark

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Acute ischemic stroke (AIS) results from occlusion of a cervical or cerebral artery and may cause significant neurologic deficits. Treatments for AIS include intravenous thrombolysis or endovascular thrombectomy, and both of these treatments are guided by the time from symptom onset and non-invasive brain imaging parameters. Advanced neuroimaging techniques, such as computed tomography and magnetic resonance imaging-cerebral perfusion imaging, are predominantly used to guide AIS treatments in extended time windows (>4.5 h for intravenous thrombolysis or >6 h for endovascular thrombectomy). Here, we discuss the role of advanced neuroimaging for AIS patient treatment in extended time windows based upon the current evidence.

Original language	English (US)
Title of host publication	Ischemic Stroke Therapeutics
Subtitle of host publication	A Comprehensive Guide
Publisher	Springer International Publishing
Pages	83-89
Number of pages	7
ISBN (Electronic)	9783031499630
ISBN (Print)	9783031499623
DOIs	https://doi.org/10.1007/978-3-031-49963-0_6
State	Published - Apr 23 2024
Externally published	Yes

Keywords

Alteplase
Extended time window
Perfusion imaging
Stroke
t-PA
Tenecteplase
Thrombectomy
Thrombolysis

ASJC Scopus subject areas

General Medicine
General Agricultural and Biological Sciences
General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1007/978-3-031-49963-0_6

Cite this

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title = "Advanced imaging for extended window stroke therapy",

abstract = "Acute ischemic stroke (AIS) results from occlusion of a cervical or cerebral artery and may cause significant neurologic deficits. Treatments for AIS include intravenous thrombolysis or endovascular thrombectomy, and both of these treatments are guided by the time from symptom onset and non-invasive brain imaging parameters. Advanced neuroimaging techniques, such as computed tomography and magnetic resonance imaging-cerebral perfusion imaging, are predominantly used to guide AIS treatments in extended time windows (>4.5 h for intravenous thrombolysis or >6 h for endovascular thrombectomy). Here, we discuss the role of advanced neuroimaging for AIS patient treatment in extended time windows based upon the current evidence.",

keywords = "Alteplase, Extended time window, Perfusion imaging, Stroke, t-PA, Tenecteplase, Thrombectomy, Thrombolysis",

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doi = "10.1007/978-3-031-49963-0\_6",

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T1 - Advanced imaging for extended window stroke therapy

AU - Heit, Jeremy J.

AU - Albers, Gregory W.

AU - Wintermark, Max

PY - 2024/4/23

Y1 - 2024/4/23

N2 - Acute ischemic stroke (AIS) results from occlusion of a cervical or cerebral artery and may cause significant neurologic deficits. Treatments for AIS include intravenous thrombolysis or endovascular thrombectomy, and both of these treatments are guided by the time from symptom onset and non-invasive brain imaging parameters. Advanced neuroimaging techniques, such as computed tomography and magnetic resonance imaging-cerebral perfusion imaging, are predominantly used to guide AIS treatments in extended time windows (>4.5 h for intravenous thrombolysis or >6 h for endovascular thrombectomy). Here, we discuss the role of advanced neuroimaging for AIS patient treatment in extended time windows based upon the current evidence.

AB - Acute ischemic stroke (AIS) results from occlusion of a cervical or cerebral artery and may cause significant neurologic deficits. Treatments for AIS include intravenous thrombolysis or endovascular thrombectomy, and both of these treatments are guided by the time from symptom onset and non-invasive brain imaging parameters. Advanced neuroimaging techniques, such as computed tomography and magnetic resonance imaging-cerebral perfusion imaging, are predominantly used to guide AIS treatments in extended time windows (>4.5 h for intravenous thrombolysis or >6 h for endovascular thrombectomy). Here, we discuss the role of advanced neuroimaging for AIS patient treatment in extended time windows based upon the current evidence.

KW - Alteplase

KW - Extended time window

KW - Perfusion imaging

KW - Stroke

KW - t-PA

KW - Tenecteplase

KW - Thrombectomy

KW - Thrombolysis

UR - https://www.scopus.com/pages/publications/85205375039

UR - https://www.scopus.com/pages/publications/85205375039#tab=citedBy

U2 - 10.1007/978-3-031-49963-0_6

DO - 10.1007/978-3-031-49963-0_6

M3 - Chapter

AN - SCOPUS:85205375039

SN - 9783031499623

SP - 83

EP - 89

BT - Ischemic Stroke Therapeutics

PB - Springer International Publishing

ER -

Advanced imaging for extended window stroke therapy

Abstract

Keywords

ASJC Scopus subject areas

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