Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens

Jennifer E. Peel; Elizabeth Jardinella; Yue Qu; Jessica A. Plante; Brooke M. Mitchell; Jordyn L. Walker; Roberto P. Garofalo; Scott C. Weaver; Kenneth S. Plante; Trevor Brasel; William S. Lawrence

doi:10.1016/j.ajic.2025.02.008

Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens

Jennifer E. Peel
, Elizabeth Jardinella
, Yue Qu
, Jessica A. Plante
, Brooke M. Mitchell
, Jordyn L. Walker
, Roberto P. Garofalo
, Scott C. Weaver
, Kenneth S. Plante
, Trevor Brasel
, William S. Lawrence

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Efficient, rapid means of air decontamination are needed against widespread respiratory pathogens such as SARS-CoV-2, the virus that causes COVID-19. This study demonstrated the efficacy of advanced photohydrolysis technology in significantly reducing infectious, aerosolized SARS-CoV-2, achieving over 99% viral inactivation. Proof-of-concept assessments for respiratory syncytial virus and monkeypox virus showed similar results, suggesting broad applicability. These findings highlight the potential of the novel technology to enhance air purification and infection control strategies against multiple airborne viral pathogens.

Original language	English (US)
Pages (from-to)	726-728
Number of pages	3
Journal	American Journal of Infection Control
Volume	53
Issue number	6
DOIs	https://doi.org/10.1016/j.ajic.2025.02.008
State	Published - Jun 2025

Keywords

Air purification
Infection control
Respiratory pathogens
Viral aerosols

ASJC Scopus subject areas

Epidemiology
Health Policy
Public Health, Environmental and Occupational Health
Infectious Diseases

Access to Document

10.1016/j.ajic.2025.02.008

Cite this

Peel, J. E., Jardinella, E., Qu, Y., Plante, J. A., Mitchell, B. M., Walker, J. L., Garofalo, R. P., Weaver, S. C., Plante, K. S., Brasel, T., & Lawrence, W. S. (2025). Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens. American Journal of Infection Control, 53(6), 726-728. https://doi.org/10.1016/j.ajic.2025.02.008

Peel, JE, Jardinella, E, Qu, Y, Plante, JA, Mitchell, BM, Walker, JL, Garofalo, RP , Weaver, SC , Plante, KS, Brasel, T & Lawrence, WS 2025, 'Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens', American Journal of Infection Control, vol. 53, no. 6, pp. 726-728. https://doi.org/10.1016/j.ajic.2025.02.008

@article{0bfa353a71624876b94aa9146041926e,

title = "Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens",

abstract = "Efficient, rapid means of air decontamination are needed against widespread respiratory pathogens such as SARS-CoV-2, the virus that causes COVID-19. This study demonstrated the efficacy of advanced photohydrolysis technology in significantly reducing infectious, aerosolized SARS-CoV-2, achieving over 99\% viral inactivation. Proof-of-concept assessments for respiratory syncytial virus and monkeypox virus showed similar results, suggesting broad applicability. These findings highlight the potential of the novel technology to enhance air purification and infection control strategies against multiple airborne viral pathogens.",

keywords = "Air purification, Infection control, Respiratory pathogens, Viral aerosols",

author = "Peel, \{Jennifer E.\} and Elizabeth Jardinella and Yue Qu and Plante, \{Jessica A.\} and Mitchell, \{Brooke M.\} and Walker, \{Jordyn L.\} and Garofalo, \{Roberto P.\} and Weaver, \{Scott C.\} and Plante, \{Kenneth S.\} and Trevor Brasel and Lawrence, \{William S.\}",

note = "Publisher Copyright: {\textcopyright} 2025 Association for Professionals in Infection Control and Epidemiology, Inc.",

year = "2025",

month = jun,

doi = "10.1016/j.ajic.2025.02.008",

language = "English (US)",

volume = "53",

pages = "726--728",

journal = "American Journal of Infection Control",

issn = "0196-6553",

publisher = "Elsevier Inc.",

number = "6",

}

TY - JOUR

T1 - Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens

AU - Peel, Jennifer E.

AU - Jardinella, Elizabeth

AU - Qu, Yue

AU - Plante, Jessica A.

AU - Mitchell, Brooke M.

AU - Walker, Jordyn L.

AU - Garofalo, Roberto P.

AU - Weaver, Scott C.

AU - Plante, Kenneth S.

AU - Brasel, Trevor

AU - Lawrence, William S.

PY - 2025/6

Y1 - 2025/6

N2 - Efficient, rapid means of air decontamination are needed against widespread respiratory pathogens such as SARS-CoV-2, the virus that causes COVID-19. This study demonstrated the efficacy of advanced photohydrolysis technology in significantly reducing infectious, aerosolized SARS-CoV-2, achieving over 99% viral inactivation. Proof-of-concept assessments for respiratory syncytial virus and monkeypox virus showed similar results, suggesting broad applicability. These findings highlight the potential of the novel technology to enhance air purification and infection control strategies against multiple airborne viral pathogens.

AB - Efficient, rapid means of air decontamination are needed against widespread respiratory pathogens such as SARS-CoV-2, the virus that causes COVID-19. This study demonstrated the efficacy of advanced photohydrolysis technology in significantly reducing infectious, aerosolized SARS-CoV-2, achieving over 99% viral inactivation. Proof-of-concept assessments for respiratory syncytial virus and monkeypox virus showed similar results, suggesting broad applicability. These findings highlight the potential of the novel technology to enhance air purification and infection control strategies against multiple airborne viral pathogens.

KW - Air purification

KW - Infection control

KW - Respiratory pathogens

KW - Viral aerosols

UR - https://www.scopus.com/pages/publications/85219104971

UR - https://www.scopus.com/pages/publications/85219104971#tab=citedBy

U2 - 10.1016/j.ajic.2025.02.008

DO - 10.1016/j.ajic.2025.02.008

M3 - Article

C2 - 39971198

AN - SCOPUS:85219104971

SN - 0196-6553

VL - 53

SP - 726

EP - 728

JO - American Journal of Infection Control

JF - American Journal of Infection Control

IS - 6

ER -

Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this