Advancing drug discovery for schizophrenia

Stephen R. Marder, Bryan Roth, Patrick F. Sullivan, Edward M. Scolnick, Eric J. Nestler, Mark A. Geyer, Daniel R. Welnberger, Maria Karayiorgou, Alessandro Guidotti, Jay Gingrich, Schahram Akbarian, Robert W. Buchanan, Jeffrey A. Lieberman, P. Jeffrey Conn, Stephen J. Haggarty, Amanda J. Law, Brian Campbell, John H. Krystal, Bita Moghaddam, Akira SawMarc G. Caron, Susan R. George, John A. Allen, Michelle Solis

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Sponsored by the New York Academy of Sciences and with support from the National Institute of Mental Health, the Life Technologies Foundation, and the Josiah Macy Jr. Foundation, "Advancing Drug Discovery for Schizophrenia" was held March 9-11 at the New York Academy of Sciences in New York City. The meeting, comprising individual talks and panel discussions, highlighted basic, clinical, and translational research approaches, all of which contribute to the overarching goal of enhancing the pharmaceutical armamentarium for treating schizophrenia. This report surveys work by the vanguard of schizophrenia research in such topics as genetic and epigenetic approaches; small molecule therapeutics; and the relationships between target genes, neuronal function, and symptoms of schizophrenia.

Original languageEnglish (US)
Pages (from-to)30-43
Number of pages14
JournalAnnals of the New York Academy of Sciences
Volume1236
Issue number1
DOIs
StatePublished - Oct 2011
Externally publishedYes

Keywords

  • GWAS
  • Genetics
  • Neuronal function
  • Schizophrenia
  • Small molecules
  • Therapeutics

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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  • Cite this

    Marder, S. R., Roth, B., Sullivan, P. F., Scolnick, E. M., Nestler, E. J., Geyer, M. A., Welnberger, D. R., Karayiorgou, M., Guidotti, A., Gingrich, J., Akbarian, S., Buchanan, R. W., Lieberman, J. A., Conn, P. J., Haggarty, S. J., Law, A. J., Campbell, B., Krystal, J. H., Moghaddam, B., ... Solis, M. (2011). Advancing drug discovery for schizophrenia. Annals of the New York Academy of Sciences, 1236(1), 30-43. https://doi.org/10.1111/j.1749-6632.2011.06216.x