Advantages of isotopic depletion of proteins for hydrogen/deuterium exchange experiments monitored by mass spectrometry

Keyphrases

• Mass Spectrometry 100%
• Hydrogen-deuterium Exchange 100%
• Isotopic Depletion 100%
• Proteolytic Fragments 66%
• Isotopic Distribution 66%
• Isomeric 66%
• Protein-protein Interaction 33%
• X-ray Crystallography 33%
• Conformational Change 33%
• Signal-to-noise Ratio 33%
• Nuclear Magnetic Resonance 33%
• Protein Subunit 33%
• Protein Complex 33%
• Biological Systems 33%
• Protease 33%
• Gas Phase 33%
• Fragment Ions 33%
• Mass Spectra 33%
• High Protein 33%
• Mass Spectrometry Methods 33%
• Solution Phase 33%
• Deuteration 33%
• Tandem Mass Spectrometry 33%
• Isobaric 33%
• Medium Size 33%
• Exchange Data 33%
• Data Reduction 33%
• Natural Abundance 33%
• Abundance Distribution 33%
• Deuterium 33%
• Peak Overlap 33%
• Multiple Deuteration 33%
• Protein Molecular Weight 33%
• Autolysis 33%

Biochemistry, Genetics and Molecular Biology

• Mass Spectrometry 100%
• Hydrogen-Deuterium Exchange 100%
• Solution and Solubility 33%
• Magnetism 33%
• Conformational Change 33%
• Protein Interaction 33%
• Molecular Weight 33%
• Signal Noise Ratio 33%
• Protein Subunit 33%
• Protein Complexes 33%
• X-Ray Crystallography 33%
• Tandem Mass Spectrometry 33%
• Protease 33%

Chemistry

• Mass Spectrometry 100%
• Hydrogen 100%
• proteolytic 66%
• Tandem Mass Spectrometry 33%
• NMR Spectroscopy 33%
• Protein Interaction 33%
• Molecular Mass 33%
• X-Ray Crystallography 33%
• Signal-to-Noise Ratio 33%