Agent of disease contracted from green monkeys

Robert E. Kissling, Roslyn Q. Robinson, Frederick A. Murphy, Sylvia G. Whitfield

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

An infectious agent obtained from patients who became ill after exposure to tissues of African green monkeys is viral in character. By electron microscopy, the agent appeared cylindrical, 90 to 100 nanometers in diameter, and 130 to 2600 nanometers in length. Cross-striations at 5-nanometer intervals and a core diameter of 45 nanometers were observed. The agent was completely resistant to the effects of the metabolic inhibitor 5-bromodeoxyuridine, which may mean that RNA is the genetic material. It was sensitive to ether and relatively sensitive to destruction by heat.

Original languageEnglish (US)
Pages (from-to)888-890
Number of pages3
JournalScience
Volume160
Issue number3830
StatePublished - 1968

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Cercopithecus aethiops
Proxy
Bromodeoxyuridine
Ether
Electron Microscopy
Hot Temperature
RNA
Genes

ASJC Scopus subject areas

  • General

Cite this

Kissling, R. E., Robinson, R. Q., Murphy, F. A., & Whitfield, S. G. (1968). Agent of disease contracted from green monkeys. Science, 160(3830), 888-890.

Agent of disease contracted from green monkeys. / Kissling, Robert E.; Robinson, Roslyn Q.; Murphy, Frederick A.; Whitfield, Sylvia G.

In: Science, Vol. 160, No. 3830, 1968, p. 888-890.

Research output: Contribution to journalArticle

Kissling, RE, Robinson, RQ, Murphy, FA & Whitfield, SG 1968, 'Agent of disease contracted from green monkeys', Science, vol. 160, no. 3830, pp. 888-890.
Kissling RE, Robinson RQ, Murphy FA, Whitfield SG. Agent of disease contracted from green monkeys. Science. 1968;160(3830):888-890.
Kissling, Robert E. ; Robinson, Roslyn Q. ; Murphy, Frederick A. ; Whitfield, Sylvia G. / Agent of disease contracted from green monkeys. In: Science. 1968 ; Vol. 160, No. 3830. pp. 888-890.
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