TY - JOUR
T1 - Agent of disease contracted from green monkeys
AU - Kissling, Robert E.
AU - Robinson, Roslyn Q.
AU - Murphy, Frederick A.
AU - Whitfield, Sylvia G.
PY - 1968
Y1 - 1968
N2 - An infectious agent obtained from patients who became ill after exposure to tissues of African green monkeys is viral in character. By electron microscopy, the agent appeared cylindrical, 90 to 100 nanometers in diameter, and 130 to 2600 nanometers in length. Cross-striations at 5-nanometer intervals and a core diameter of 45 nanometers were observed. The agent was completely resistant to the effects of the metabolic inhibitor 5-bromodeoxyuridine, which may mean that RNA is the genetic material. It was sensitive to ether and relatively sensitive to destruction by heat.
AB - An infectious agent obtained from patients who became ill after exposure to tissues of African green monkeys is viral in character. By electron microscopy, the agent appeared cylindrical, 90 to 100 nanometers in diameter, and 130 to 2600 nanometers in length. Cross-striations at 5-nanometer intervals and a core diameter of 45 nanometers were observed. The agent was completely resistant to the effects of the metabolic inhibitor 5-bromodeoxyuridine, which may mean that RNA is the genetic material. It was sensitive to ether and relatively sensitive to destruction by heat.
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U2 - 10.1126/science.160.3830.888
DO - 10.1126/science.160.3830.888
M3 - Article
C2 - 4296724
AN - SCOPUS:0014428522
SN - 0036-8075
VL - 160
SP - 888
EP - 890
JO - Science
JF - Science
IS - 3830
ER -