Aggression upon adolescent cocaine exposure linked to serotonin anomalies

Theoretical comment on Ricci et al. (2004)

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Aggressive tendencies may be linked to the psychopharmacology of cocaine, yet few experimental approaches have been brought to bear on understanding the neurobiological implications of cocaine exposure during the developmentally sensitive period of adolescence. In this issue, Melloni and coauthors (L. A. Ricci, J. M. Grimes, & R. H. Melloni, 2004) present convincing evidence that the development of serotonin signal cascades in key brain regions can be disrupted by cocaine administration, resulting in an aggressive response in adolescents. These findings may allow the development of new therapeutic approaches to tailor pharmacotherapy for adolescents experiencing problems with aggressive behavior and/or impulse control associated with illicit drug use.

Original languageEnglish (US)
Pages (from-to)1143-1144
Number of pages2
JournalBehavioral Neuroscience
Volume118
Issue number5
DOIs
StatePublished - Oct 2004

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Aggression
Cocaine
Serotonin
Psychopharmacology
Street Drugs
Drug Therapy
Brain
Therapeutics

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Clinical Psychology

Cite this

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