Aldolase A Ins(1,4,5)P₃-binding domains as determined by site-directed mutagenesis

Biochemistry, Genetics and Molecular Biology

• Site-Directed Mutagenesis 100%
• Binding Domain 100%
• Aldolase A 100%
• Active Site 40%
• Static Electricity 40%
• Fructose-Bisphosphate Aldolase 40%
• Aldolase 40%
• Enzymatic Activity 40%
• Wild Type 20%
• Enzyme 20%
• Amino Acids 20%
• Binding Site 20%
• EC50 20%
• Phosphotyrosine-Binding Domain 20%
• Pleckstrin Homology Domain 20%
• Inositol 20%

Keyphrases

• Site-directed mutagenesis 100%
• Ligand-binding Domain 100%
• Ins(1,4,5)P3 100%
• Aldolase 100%
• 6-P2 23%
• Active Sites 15%
• Catalytic Activity 15%
• Binding Site 7%
• IC50 Value 7%
• Positively Charged 7%
• Charged Residue 7%
• Evoked Release 7%
• Inositol 1,4,5-trisphosphate 7%
• Positive Charge 7%
• Electrostatic Interaction 7%
• Active Enzyme 7%
• Neutral Amino Acid 7%
• Electrostatic Binding 7%
• Pleckstrin Homology Domain 7%
• Aldolase Activity 7%
• Phosphotyrosine Binding Domains 7%
• Carbon-carbon Bond Cleavage 7%