Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in APC^min/+ mice

Medicine & Life Sciences

• fidarestat 97%
• Intestinal Polyps 82%
• Aldehyde Reductase 68%
• High Fat Diet 51%
• Large Intestine 17%
• Polyps 14%
• Small Intestine 13%
• Colorectal Neoplasms 11%
• Obesity 10%
• APC Genes 10%
• polyol 10%
• Intestinal Neoplasms 9%
• Proliferating Cell Nuclear Antigen 7%
• beta Catenin 7%
• Carcinogens 7%
• Metabolic Syndrome 6%
• Intestines 6%
• Colonic Neoplasms 6%
• Epidemiologic Studies 6%
• Insulin Resistance 5%
• Intercellular Signaling Peptides and Proteins 5%
• Carcinogenesis 5%
• Mutation 4%
• Enzymes 3%
• Pharmaceutical Preparations 3%
• Neoplasms 2%

Chemical Compounds

• Fidarestat 100%
• Aldose Reductase Inhibitor 78%
• Aldose 32%
• Chemopreventive 18%
• Polyol 13%
• Insulin Derivative 13%
• Mutation 10%
• Metabolic 10%
• Resistance 8%
• Drug 6%