Keyphrases
Hyperglycemia
100%
Aldose Reductase
100%
Human Umbilical Vein Endothelial Cells (HUVECs)
100%
Sirtuin 1 (SIRT1)
100%
MTOR Pathway
100%
High Glucose
60%
P-AMPK
40%
Endothelial Dysfunction
30%
Phosphorylation
30%
Aldose Reductase Inhibitor
30%
Mammalian Target of Rapamycin (mTOR)
20%
Fidarestat
20%
THP-1 Cells
20%
Molecular Mechanism
10%
Inducible Nitric Oxide Synthase
10%
Diabetes
10%
Growth Factors
10%
Knockdown
10%
Endothelial Cells
10%
Cell-to-cell
10%
Small Interfering RNA (siRNA)
10%
Cell Death
10%
Vascular Complications
10%
Intercellular Adhesion molecule-1 (ICAM-1)
10%
Vascular Cell Adhesion molecule-1 (VCAM-1)
10%
Adhesion
10%
Adhesion Molecules
10%
B-cell Lymphoma 2 (Bcl-2)
10%
Inflammatory Pathways
10%
Cell Viability
10%
Oxidative Signaling
10%
Cellular Expression
10%
Endothelial Nitric Oxide Synthase (eNOS)
10%
Incubation
10%
Caspase-3
10%
Aldo-keto Reductase Family 1 Member B1 (AKR1B1)
10%
ROS Generation
10%
Streptozotocin-induced Diabetic Rats
10%
Cell Inhibition
10%
SIRT1 Expression
10%
Mouse Heart
10%
Monocyte Adhesion
10%
Mouse Aorta
10%
SIRT1 Inhibitor
10%
Biochemistry, Genetics and Molecular Biology
Hyperglycemia
100%
Aldose Reductase
100%
AMP-activated Protein Kinase
100%
Mammalian Target of Rapamycin
100%
Sirtuin1
100%
Mediator
10%
Growth Factor
10%
Cytokine
10%
Cell Adhesion Proteins
10%
Cell Death
10%
Small Interfering RNA
10%
VCAM-1
10%
Cell Viability
10%
ICAM-1
10%
Caspase 3
10%
Pharmacology, Toxicology and Pharmaceutical Science
Hyperglycemia
100%
Aldehyde Reductase
100%
Endothelial Dysfunction
30%
Fidarestat
20%
Growth Factor
10%
Diabetes Mellitus
10%
Cytokine
10%
Small Interfering RNA
10%
Vascular Cell Adhesion Molecule 1
10%
Caspase 3
10%
Cell Viability
10%
Intercellular Adhesion Molecule 1
10%
Cell Adhesion Proteins
10%