Allostery in rabbit pyruvate kinase: Development of a strategy to elucidate the mechanism

Keyphrases

• Allosteric Regulation 10%
• Allostery 100%
• Amino Acid Variation 10%
• Amino Acids 10%
• C Domain 10%
• Distance Geometry 10%
• Electrostatic Interaction 10%
• Escherichia Coli 10%
• Fantom 10%
• Far-UV CD 10%
• Force Field 10%
• Four-helix Bundle 10%
• Homology Modeling 10%
• Hydrogen Bonds (H-bonds) 10%
• Interfacial Contact 10%
• Isozymes 20%
• Kidney 20%
• Kinase Protein 10%
• Kinase Structure 10%
• Loop Conformation 30%
• Low Affinity 10%
• One-loop 10%
• Packing Interactions 10%
• Phenylalanine 10%
• Phosphoenolpyruvate 10%
• Proline 10%
• Pyruvate Kinase 100%
• Rabbit muscle 20%
• RNA Splicing 10%
• Salt Bridge 30%
• Sedimentation Velocity 10%
• Self-correcting 10%
• Site-directed mutagenesis 10%
• Steady-state Kinetics 10%
• Subunit Interface 10%
• Tetrameric Structure 10%
• X-ray Structure 10%

Biochemistry, Genetics and Molecular Biology

• Allosteric Regulation 100%
• Alternative Splicing 10%
• Amino Acids 20%
• Biochemistry 10%
• Conformation 40%
• Crystal Structure 10%
• Escherichia coli 10%
• Helix Bundle 10%
• Isozyme 20%
• Leporidae 100%
• Phenylalanine 10%
• Proline 10%
• Protein Kinase 10%
• Pyruvate Kinase 100%
• Sedimentation Rate 10%
• Serine 10%
• Site-Directed Mutagenesis 10%
• Static Electricity 10%
• Steady State 10%
• Wild Type 10%
• X Ray 10%