@article{2c7d02a827fa4ac89d379bb150365bc1,
title = "Allpahuayo virus: A newly recognized arenavirus (Arenaviridae) from arboreal rice rats (Oecomys Bicolor and Oecomys Paricola) in Northeastern Peru",
abstract = "Allpahuayo virus was initially isolated from arboreal rice rats (Oecomys bicolor and Oecomys paricola) collected during 1997 at the Allpahuayo Biological Station in northeastern Peru. Serological and genetic studies identified the virus as a new member of the Tacaribe complex of the genus Arenavirus. The small (S) segment of the Allpahuayo virus prototype strain CLHP-2098 (Accession No. AY012686) was sequenced, as well as that of sympatric isolate CLHP-2472 (Accession No. AY012687), from the same rodent species. The S segment was 3382 bases in length and phylogenetic analysis indicated that Allpahuayo is a sister virus to Pichinde in clade A. Two embisense, nonoverlapping reading frames were identified, which result in two predicted gene products, a glycoprotein precursor (GPC) and a nucleocapsid protein (NP). A predicted stable single hairpin secondary structure was identified in the intergenic region between GPC and NP. Details of the genetic organization of Allpahuayo virus are discussed.",
keywords = "Allpahuayo virus, Arenavirus, Peru, Rice rats, S segment, Zoonoses",
author = "Moncayo, {Abelardo C.} and Hice, {Christine L.} and Watts, {Douglas M.} and {Travassos De Rosa}, {Amelia P.A.} and Hilda Guzman and Russell, {Kevin L.} and Carlos Calampa and Alfonso Gozalo and Popov, {Vsevolod L.} and Weaver, {Scott C.} and Tesh, {Robert B.}",
note = "Funding Information: We thank Victor Montrueil, former manager of the Instituto de Inves-tigaciones de la Amazonia Peruana (IIAP), for permission to trap animals at the Allpahuayo Biological Station; Arturo Chavez for assistance in the field; personnel in the Mammology Department of the Museo de Historia Natural of San Marcos University in Lima for help in identifying many of the mammal specimens; Carolina Guevara and Karla Block, Naval Medical Research Center Detachment, for help in packing and shipping the samples from Peru; Guy Musser and Robert Voss of the American Museum of Natural History, New York, for the identification of the Oecomys specimens; Remi N. Charrel for his expert advice on phylogenetic analyses; and Violet C. Han for assistance in electron microscopy. This research was supported in part by NIH Grants AI 10984 and AI 39800, and by U.S. Naval Medical Research and Development Command NNMC, Bethesda, MD, Work Unit 61102A.S13.T.B006.8615. The opinions and assertions contained herein are the private ones of the writers and are not to be construed as official or as reflecting the view of the Navy Department or the naval service at large.",
year = "2001",
month = jun,
day = "5",
doi = "10.1006/viro.2000.0803",
language = "English (US)",
volume = "284",
pages = "277--286",
journal = "Virology",
issn = "0042-6822",
publisher = "Academic Press Inc.",
number = "2",
}