Alterations in pituitary gland volume in polycystic ovary syndrome: A structural magnetic resonance imaging study

Ebru Unlu; Bekir Serdar Unlu; Ozan Turamanlar; Mehtap Beker Acay; Emre Kacar; Yunus Yildiz; Ozgur Verim; Nazan Okur; Cinar Balcik; Suleyman Tasgetiren; Aylin Yucel

doi:10.1016/j.clinimag.2014.10.002

Alterations in pituitary gland volume in polycystic ovary syndrome: A structural magnetic resonance imaging study

Ebru Unlu, Bekir Serdar Unlu, Ozan Turamanlar, Mehtap Beker Acay, Emre Kacar, Yunus Yildiz, Ozgur Verim, Nazan Okur, Cinar Balcik, Suleyman Tasgetiren, Aylin Yucel

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The purpose of this prospectively designed cross-sectional observational study was to evaluate the effect of polycystic ovary syndrome (PCOS) on pituitary gland volume (PGV) under the hypothesis that endocrinologic changes may lead to morphologic changes of the pituitary gland. Twenty-six PCOS patients and 31 control subjects underwent magnetic resonance imaging (MRI) of the pituitary. Informed consent was obtained from all subjects. PGV was significantly larger in PCOS patients than in control subjects. Luteinizing hormone/follicle-stimulating hormone ratio was the only predictor of PGV. The association between pituitary gland enlargement and PCOS should be kept in mind when pituitary hypertrophy is detected on MRI.

Original language	English (US)
Pages (from-to)	449-453
Number of pages	5
Journal	Clinical Imaging
Volume	39
Issue number	3
DOIs	https://doi.org/10.1016/j.clinimag.2014.10.002
State	Published - May 1 2015
Externally published	Yes

Keywords

Magnetic resonance imaging
Mean ovarian volume
Pituitary gland volume
Polycystic ovary syndrome

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1016/j.clinimag.2014.10.002

Cite this

@article{fc0e4bb1d33c40a88a2b5e60563aaeda,

title = "Alterations in pituitary gland volume in polycystic ovary syndrome: A structural magnetic resonance imaging study",

abstract = "The purpose of this prospectively designed cross-sectional observational study was to evaluate the effect of polycystic ovary syndrome (PCOS) on pituitary gland volume (PGV) under the hypothesis that endocrinologic changes may lead to morphologic changes of the pituitary gland. Twenty-six PCOS patients and 31 control subjects underwent magnetic resonance imaging (MRI) of the pituitary. Informed consent was obtained from all subjects. PGV was significantly larger in PCOS patients than in control subjects. Luteinizing hormone/follicle-stimulating hormone ratio was the only predictor of PGV. The association between pituitary gland enlargement and PCOS should be kept in mind when pituitary hypertrophy is detected on MRI.",

keywords = "Magnetic resonance imaging, Mean ovarian volume, Pituitary gland volume, Polycystic ovary syndrome",

author = "Ebru Unlu and Unlu, {Bekir Serdar} and Ozan Turamanlar and Acay, {Mehtap Beker} and Emre Kacar and Yunus Yildiz and Ozgur Verim and Nazan Okur and Cinar Balcik and Suleyman Tasgetiren and Aylin Yucel",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = may,

day = "1",

doi = "10.1016/j.clinimag.2014.10.002",

language = "English (US)",

volume = "39",

pages = "449--453",

journal = "Clinical Imaging",

issn = "0899-7071",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Alterations in pituitary gland volume in polycystic ovary syndrome

T2 - A structural magnetic resonance imaging study

AU - Unlu, Ebru

AU - Unlu, Bekir Serdar

AU - Turamanlar, Ozan

AU - Acay, Mehtap Beker

AU - Kacar, Emre

AU - Yildiz, Yunus

AU - Verim, Ozgur

AU - Okur, Nazan

AU - Balcik, Cinar

AU - Tasgetiren, Suleyman

AU - Yucel, Aylin

PY - 2015/5/1

Y1 - 2015/5/1

N2 - The purpose of this prospectively designed cross-sectional observational study was to evaluate the effect of polycystic ovary syndrome (PCOS) on pituitary gland volume (PGV) under the hypothesis that endocrinologic changes may lead to morphologic changes of the pituitary gland. Twenty-six PCOS patients and 31 control subjects underwent magnetic resonance imaging (MRI) of the pituitary. Informed consent was obtained from all subjects. PGV was significantly larger in PCOS patients than in control subjects. Luteinizing hormone/follicle-stimulating hormone ratio was the only predictor of PGV. The association between pituitary gland enlargement and PCOS should be kept in mind when pituitary hypertrophy is detected on MRI.

AB - The purpose of this prospectively designed cross-sectional observational study was to evaluate the effect of polycystic ovary syndrome (PCOS) on pituitary gland volume (PGV) under the hypothesis that endocrinologic changes may lead to morphologic changes of the pituitary gland. Twenty-six PCOS patients and 31 control subjects underwent magnetic resonance imaging (MRI) of the pituitary. Informed consent was obtained from all subjects. PGV was significantly larger in PCOS patients than in control subjects. Luteinizing hormone/follicle-stimulating hormone ratio was the only predictor of PGV. The association between pituitary gland enlargement and PCOS should be kept in mind when pituitary hypertrophy is detected on MRI.

KW - Magnetic resonance imaging

KW - Mean ovarian volume

KW - Pituitary gland volume

KW - Polycystic ovary syndrome

UR - http://www.scopus.com/inward/record.url?scp=84927949760&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84927949760&partnerID=8YFLogxK

U2 - 10.1016/j.clinimag.2014.10.002

DO - 10.1016/j.clinimag.2014.10.002

M3 - Article

C2 - 25457522

AN - SCOPUS:84927949760

SN - 0899-7071

VL - 39

SP - 449

EP - 453

JO - Clinical Imaging

JF - Clinical Imaging

IS - 3

ER -

Alterations in pituitary gland volume in polycystic ovary syndrome: A structural magnetic resonance imaging study

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this