Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons

Keyphrases

• Alzheimer's Disease Brain 100%
• Extracellular Vesicles 100%
• Brain-inspired 100%
• Interneuron 100%
• Tau Pathology 100%
• Alzheimer's Disease 50%
• Prodromal Alzheimer's Disease 33%
• Glutamic Acid Decarboxylase 65 (GAD65) 25%
• GABAergic Interneurons 16%
• Inoculation 16%
• Misfolding 16%
• Tau Oligomers 16%
• Novel Mechanism 8%
• Epitope 8%
• Oligomeric 8%
• Hippocampus 8%
• Atomic Force Microscopy 8%
• Patch-clamp Recording 8%
• Human Brain 8%
• C-Fos 8%
• Sarkosyl 8%
• Phosphorylated tau 8%
• Non-demented 8%
• C57BL 8%
• Neuronal Dysfunction 8%
• GABAergic 8%
• Dentate Gyrus 8%
• Cortical Neurons 8%
• Punctum 8%
• Parahippocampal Region 8%
• Pyramidal Neurons 8%
• CA1 Region 8%
• Dot Blot 8%
• CA1 Pyramidal Cells 8%
• Tau Fibrils 8%
• Molecular Layer 8%
• GABAergic Transmission 8%
• Physicochemical Structure 8%
• Propagation of tau Pathology 8%
• Spontaneous Inhibitory Postsynaptic Currents 8%
• Glutamate Receptor 2 8%
• Abnormally Phosphorylated tau 8%
• Mossy Cell 8%
• Tau Propagation 8%

Neuroscience

• Alzheimer's Disease 100%
• Interneuron 100%
• Glutamate Decarboxylase 67 27%
• Oligomer 18%
• In Vitro 9%
• Epitope 9%
• Patch Clamp Technique 9%
• Hippocampus 9%
• C-Fos 9%
• Pyramidal Cell 9%
• Dentate Gyrus 9%
• GABAergic Transmission 9%
• Glutamate Receptor 2 9%
• Human Brain 9%
• C57BL 6 Mouse 9%

Biochemistry, Genetics and Molecular Biology

• Tau 100%
• Interneuron 100%
• Glutamate Decarboxylase 23%
• Atomic Force Microscopy 7%
• Sarkosyl 7%
• C-Fos 7%
• Whole Cell Patch Clamp 7%
• Glutamate Receptor 7%
• C57BL 6 Mouse 7%
• Patch Clamp Technique 7%
• Dot Blot 7%
• GABAergic Transmission 7%
• Pyramidal Cell 7%