Amino acid substitutions resulting from suppression of nonsense mutations. IV. Leucine insertion by the Su6+ suppressor gene

Teh sheng Chan, Alan Garen

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Suppression of an alkaline phosphatase amber mutant by the Su6+ suppressor gene results in the substitution of leucine for a tryptophan residue in the phosphatase molecule. Thus, the Su6+ gene causes the amber triplet UAG to code for leucine. This is the fifth amino acid that can be specified by UAG as a result of suppression by different suppressor genes.

Original languageEnglish (US)
Pages (from-to)545-548
Number of pages4
JournalJournal of Molecular Biology
Volume45
Issue number3
DOIs
StatePublished - Nov 14 1969
Externally publishedYes

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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