Amino acid substitutions resulting from suppression of nonsense mutations. IV. Leucine insertion by the Su6+ suppressor gene

Teh sheng Chan, Alan Garen

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Suppression of an alkaline phosphatase amber mutant by the Su6+ suppressor gene results in the substitution of leucine for a tryptophan residue in the phosphatase molecule. Thus, the Su6+ gene causes the amber triplet UAG to code for leucine. This is the fifth amino acid that can be specified by UAG as a result of suppression by different suppressor genes.

Original languageEnglish (US)
Pages (from-to)545-548
Number of pages4
JournalJournal of Molecular Biology
Volume45
Issue number3
StatePublished - Nov 14 1969
Externally publishedYes

Fingerprint

Amber
Suppressor Genes
Nonsense Codon
Amino Acid Substitution
tryptophan-leucine
Leucine
Phosphoric Monoester Hydrolases
Alkaline Phosphatase
Amino Acids
Genes

ASJC Scopus subject areas

  • Virology

Cite this

Amino acid substitutions resulting from suppression of nonsense mutations. IV. Leucine insertion by the Su6+ suppressor gene. / Chan, Teh sheng; Garen, Alan.

In: Journal of Molecular Biology, Vol. 45, No. 3, 14.11.1969, p. 545-548.

Research output: Contribution to journalArticle

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