Amino acid substitutions resulting from suppression of nonsense mutations. IV. Leucine insertion by the Su6+ suppressor gene

Teh sheng Chan; Alan Garen

doi:10.1016/0022-2836(69)90311-8

Amino acid substitutions resulting from suppression of nonsense mutations. IV. Leucine insertion by the Su6⁺ suppressor gene

Teh sheng Chan
, Alan Garen

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Suppression of an alkaline phosphatase amber mutant by the Su6⁺ suppressor gene results in the substitution of leucine for a tryptophan residue in the phosphatase molecule. Thus, the Su6⁺ gene causes the amber triplet UAG to code for leucine. This is the fifth amino acid that can be specified by UAG as a result of suppression by different suppressor genes.

Original language	English (US)
Pages (from-to)	545-548
Number of pages	4
Journal	Journal of Molecular Biology
Volume	45
Issue number	3
DOIs	https://doi.org/10.1016/0022-2836(69)90311-8
State	Published - Nov 14 1969
Externally published	Yes

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1016/0022-2836(69)90311-8

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abstract = "Suppression of an alkaline phosphatase amber mutant by the Su6+ suppressor gene results in the substitution of leucine for a tryptophan residue in the phosphatase molecule. Thus, the Su6+ gene causes the amber triplet UAG to code for leucine. This is the fifth amino acid that can be specified by UAG as a result of suppression by different suppressor genes.",

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AB - Suppression of an alkaline phosphatase amber mutant by the Su6+ suppressor gene results in the substitution of leucine for a tryptophan residue in the phosphatase molecule. Thus, the Su6+ gene causes the amber triplet UAG to code for leucine. This is the fifth amino acid that can be specified by UAG as a result of suppression by different suppressor genes.

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Amino acid substitutions resulting from suppression of nonsense mutations. IV. Leucine insertion by the Su6⁺ suppressor gene

Abstract

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