An electron dense extracellular material in the nervous system of Aplysia

R. E. Coggeshall

Research output: Contribution to journalArticle


An electron dense material is found in the extracellular space of the nervous system of Aplysia, a marine mollusc whose ganglia are widely studied by neurobiologists. This material appears to consist of irregular electrondense granules, with diameters of approximately 600 Å. This material is found between the glial cells that surround the neuronal perikarya. It is not found in other regions of the nervous system. Because it is found in the ganglion cell layer of the nervous system and because the neurons contain what may be the precursor of this substance, the electron-dense material is regarded as most probably being a neuronal product. The importance of this material is that it is one of the few examples of visible structure in the extracellular space of the nervous system.

Original languageEnglish (US)
Pages (from-to)281-289
Number of pages9
JournalAnatomical Record
Issue number3
StatePublished - 1977
Externally publishedYes


ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Anatomy

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